Trial reportThe Journal of international medical research2019
Effects of periodontal therapy on eradication and recurrence of Helicobacter pylori infection after successful treatment.
Trial report in The Journal of international medical research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Possible Association of Periodontal Diseases WithFrontiers in medicine · 2022Pooled it
- Novel MAXPOWER biological antibacterial liquid for eradicating oral Helicobacter pylori.BMC infectious diseases · 2024Trial
- Barriers toBMJ open · 2026Article
- BeyondMedicina (Kaunas, Lithuania) · 2025Review
- Effect of nonsurgical periodontal therapy on the eradication of gastricJournal of advanced periodontology & implant dentistry · 2025Article
- Review of foodborne helicobacteriosis.Italian journal of food safety · 2024Review
- Diagnostic Methods for Helicobacter pylori.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2024Review
- Characterization of the unique oral microbiome of children harboringJournal of oral microbiology · 2024Article
- Use of eradication therapy in adjunction to periodontal therapy versus alone for treatment ofAnnals of medicine and surgery (2012) · 2023Article
- Association of Chronic Periodontitis with Helicobacter pylori Infection in Stomach or Mouth: A Systematic Review and Meta-Analysis.European journal of dentistry · 2023Article
- Analysis of Genetic Relatedness between Gastric and OralInternational journal of molecular sciences · 2023Article
- Detection ofMicroorganisms · 2022Article
- Review
- Article
- [Combined detection ofNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021Article
- Higher Risk of GastricInternational journal of environmental research and public health · 2021Article
- Distribution ofBiomedicines · 2020Article
- Precancerous Gastric Lesions withBioMed research international · 2020Article
- Long-term follow-up ofEmerging microbes & infections · 2020Observational
- Helicobacter pylori recrudescence and its influencing factors.Journal of cellular and molecular medicine · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study aimed to evaluate the effects of periodontal therapy on the efficacy of Helicobacter pylori eradication and on the recurrence of infection after eradication.
methodsWe conducted a prospective randomized trial on 698 gastric H. pylori-infected patients, of whom 347 received gastric H. pylori treatment alone and 342 received gastric H. pylori treatment plus periodontal therapy. The presence of H. pylori and associated virulence genes were detected by real-time polymerase chain reaction.
resultsAfter eradication of gastric H. pylori infection, the recurrence of gastric H. pylori was significantly lower in the gastric H. pylori treatment plus periodontal therapy group than in the group receiving gastric H. pylori treatment alone (OR 0.67; 95% CI 0.45 to 0.99), whereas the eradication rate was not significantly different (OR 0.87; 95% CI 0.68 to 0.98). There was a close relationship between the presence of H. pylori in saliva and its presence in the stomach.
conclusionsThe oral cavity is an important reservoir for gastric H. pylori infection. Adjunctive periodontal therapy could enhance the efficiency of H. pylori treatment and reduce the recurrence of gastric H. pylori infection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.