Evidence map›Paper›PMID 30616424›Full record

ArticleThe Journal of international medical research2019

Effect of neurocentral cartilage destruction on spinal growth in immature rabbits.

Jie Wen, Dahui Wang, Ke Fang, Sheng Xiao, Ruixue Ma, Hong Liu

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Digital anatomical features of morphological development in the atlantoaxial synchondroses in children aged 1 to 6 years old: a retrospective study of CT images.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jie Wen1 Department of Orthopedics, The Children's Hospital of Fudan University, Shanghai, China.
Dahui Wang1 Department of Orthopedics, The Children's Hospital of Fudan University, Shanghai, China.
Ke Fang2 Department of Pediatric Orthopaedics, Hunan Provincial People's Hospital, the First Affiliated Hospital of Hunan Normal University, Changsha, Hunan, China.
Sheng Xiao2 Department of Pediatric Orthopaedics, Hunan Provincial People's Hospital, the First Affiliated Hospital of Hunan Normal University, Changsha, Hunan, China.
Ruixue Ma1 Department of Orthopedics, The Children's Hospital of Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0003-0401-906X
Hong Liu2 Department of Pediatric Orthopaedics, Hunan Provincial People's Hospital, the First Affiliated Hospital of Hunan Normal University, Changsha, Hunan, China.
Hunan Normal University · CNChildren's Hospital of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study was performed to observe the effect of neurocentral cartilage (NCC) destruction on spinal growth in immature rabbits.

methodsThe NCC of the lumbar vertebrae of 24 4-week-old female rabbits was destroyed through posterolateral and anterior approaches, and three-dimensional computed tomography examinations were performed 3 months after the procedure.

resultsScoliosis was successfully induced in all rabbits of both the anterior and posterolateral approach groups. The scoliosis exceeded 10 degrees in three rabbits, which exhibited coronal scoliosis of the spine, unequal length and thickness of the bilateral pedicles, and rotation of the vertebrae. Scoliosis was not observed in the control group.

conclusionsDestruction of the unilateral NCC in immature rabbits can induce structural scoliosis, similar to the pathological features of human scoliosis. The Cobb angles are similar after NCC destruction by a posterolateral approach and under direct vision via the anterior approach.

Indexed as

AnimalsCartilageFemaleLumbar VertebraeRabbitsScoliosisSpineThoracic VertebraeCobb anglecomputed tomographyetiologyneurocentral cartilagerabbitsScoliosis

Identifiers

PMID30616424
PMCPMC6381499
OpenAlexW2910346205

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.