Evidence map›Paper›PMID 30615854›Full record

ArticleClinica chimica acta; international journal of clinical chemistry2019

Validation of a liquid chromatography-tandem mass spectrometry method for analyzing cannabinoids in oral fluid.

Philip M Sobolesky, Breland E Smith, Jacqueline A Hubbard, Judy Stone, Thomas D Marcotte, David J Grelotti, Igor Grant, Robert L Fitzgerald

Registry-linked trialAbstract readValidation Study
In one paragraph

Article in Clinica chimica acta; international journal of clinical chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02849587 (A Randomized, Controlled Trial of Cannabis in Healthy Volunteers Evaluating Simulated Driving, Field Performance Tests and Cannabinoid Levels), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02849587 phase1 / phase2completednot on this map

A Randomized, Controlled Trial of Cannabis in Healthy Volunteers Evaluating Simulated Driving, Field Performance Tests and Cannabinoid Levels

TypeinterventionalSponsorUniversity of California, San DiegoRan2017 to 2019Enrolled199ConditionsCannabis IntoxicationArmsCannabis
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Article
  3. Cannabidiol mitigates alcohol dependence and withdrawal with neuroprotective effects in the basolateral amygdala and striatum.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Screening Method for the Quality Evaluation of Cannabidiols in Water-based Products Using Liquid Chromatography Tandem Mass Spectrometry.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Philip M SoboleskyDepartment of Pathology, Center for Advanced Laboratory Medicine, University of California, San Diego Health, San Diego, CA, USA. Electronic address: philip.sobolesky@hhs.sccgov.org.
Breland E SmithDepartment of Pathology, Center for Advanced Laboratory Medicine, University of California, San Diego Health, San Diego, CA, USA; Insource Diagnostics, Monrovia, CA, USA.
Jacqueline A HubbardDepartment of Pathology, Center for Advanced Laboratory Medicine, University of California, San Diego Health, San Diego, CA, USA.
Judy StoneDepartment of Pathology, Center for Advanced Laboratory Medicine, University of California, San Diego Health, San Diego, CA, USA.
Thomas D MarcotteDepartment of Psychiatry, Center for Medicinal Cannabis Research, University of California San Diego, San Diego, CA, USA.
David J GrelottiDepartment of Psychiatry, Center for Medicinal Cannabis Research, University of California San Diego, San Diego, CA, USA.
Igor GrantDepartment of Psychiatry, Center for Medicinal Cannabis Research, University of California San Diego, San Diego, CA, USA.
Robert L FitzgeraldDepartment of Pathology, Center for Advanced Laboratory Medicine, University of California, San Diego Health, San Diego, CA, USA.

Funding

STRUCTURAL NEUROIMAGING COREP30MH062512 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jessica Lynette Montoya · 2001 to 2026
$50.4M
NIMH NIH HHS P30 MH062512
6 · The paper itself

Abstract

A liquid chromatography tandem mass spectrometry method was developed for quantifying ten cannabinoids in oral fluid (OF). This method utilizes OF collected by the Quantisal™ device and concurrently quantifies cannabinol (CBN), cannabidiol (CBD), Δ

Indexed as

Body FluidsCalibrationCannabinoidsChromatography, LiquidClinical Chemistry TestsHumansLinear ModelsTandem Mass SpectrometryCannabinoidsCannabinoidOral fluidTandem mass spectrometryTHC

Identifiers

PMID30615854
PMCPMC10885733

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.