Evidence map›Paper›PMID 30615666›Full record

Trial reportPloS one2019

Comparative effectiveness of aerobic, resistance, and combined training on cardiovascular disease risk factors: A randomized controlled trial.

Elizabeth C Schroeder, Warren D Franke, Rick L Sharp, Duck-Chul Lee

Open access · goldAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 129 papers, 22 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
129citing papers in PubMed, 22 pooled it
30.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

129 citing papers in PubMed, 22 syntheses or guidelines pooled it, 265 citations in OpenAlex.

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  15. Meta-Analysis of the Effect of Different Exercise Mode on Carotid Atherosclerosis.International journal of environmental research and public health · 2023
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  20. Effect of different types of regular exercise on physical fitness in adults with overweight or obesity: Systematic review and meta-analyses.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021
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69 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Elizabeth C SchroederDepartment of Kinesiology and Nutrition, University of Illinois, Chicago, IL, United States of America.
Warren D FrankeDepartment of Kinesiology, Iowa State University, Ames, IA, United States of America.
Rick L SharpDepartment of Kinesiology, Iowa State University, Ames, IA, United States of America.ORCID 0000-0002-4637-6156
Duck-Chul LeeDepartment of Kinesiology, Iowa State University, Ames, IA, United States of America.ORCID 0000-0001-6423-5341
Iowa State University · USUniversity of Illinois Chicago · US

Funding

Comparison of the Cardiovascular Benefits of Resistance, Aerobic, and Combined Exercise (Cardio-RACE)R01HL133069 · NHLBI · IOWA STATE UNIVERSITY · PI LEE, DUCK-CHUL · 2016 to 2020
$3.4M
NHLBI NIH HHS R01 HL133069
6 · The paper itself

Abstract

Although exercise has well-documented health benefits on cardiovascular disease (CVD), the benefit of combination exercise on CVD risk factors in individuals with elevated risk has not been fully elucidated. We compared the effects of aerobic, resistance, and a combination of both aerobic and resistance training on CVD risk factors including peripheral and central BP, cardiorespiratory fitness (CRF), muscular strength, body composition, blood glucose and lipids. Sixty-nine adults (58±7 years) with an elevated blood pressure or hypertension, overweight/obesity, and sedentary lifestyle were randomized to one of the three 8-week exercise programs or a non-exercise control group. Participants in all three exercise groups had an equal total exercise time, 3 days/week (aerobic: 60 minutes/session vs. resistance: 60 minutes/session vs. combination: aerobic 30 minutes/session plus resistance 30 minutes/session). Combined training provided significant reductions in peripheral (-4 mmHg) and central diastolic BP (-4 mmHg), increase in CRF (4.9 ml/kg/min), increase in upper (4 kg) and lower (11 kg) body strength, and increase in lean body mass (0.8 kg) (p <0.05). Aerobic training only increased CRF (7.7 ml/kg/min), and reduced body weight (-1.0 kg) and fat mass (-0.9 kg) (p <0.05). Resistance training only increased lower body strength (13 kg) and reduced waist circumference (-1.7 cm) (p <0.05). However, neither aerobic or resistance training alone showed significant reductions in BP (p>0.05). Furthermore, a composite score of CVD risk factors indicated a greater reduction with combination training compared to the control group. In conclusion, among individuals at an increased risk for CVD, as little as 8-weeks of combined training may provide more comprehensive CVD benefits compared to time-matched aerobic or resistance training alone.

Indexed as

Muscle StrengthAgedBody Mass IndexCardiorespiratory FitnessCardiovascular DiseasesCase-Control StudiesExercise TherapyFemaleHumansMaleMiddle AgedResistance TrainingRisk FactorsTime Factors

Identifiers

PMID30615666
PMCPMC6322789
OpenAlexW2906868959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.