Evidence map›Paper›PMID 30615473›Full record

ArticleAstrobiology2019

Hydroxymethanesulfonate from Volcanic Sulfur Dioxide: A "Mineral" Reservoir for Formaldehyde and Other Simple Carbohydrates in Prebiotic Chemistry.

J Kawai, D Chris McLendon, H-J Kim, S A Benner

Abstract read
In one paragraph

Article in Astrobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. The Formose Reaction with SOLife (Basel, Switzerland) · 2026
    Article
  2. Interstep compatibility of a model for the prebiotic synthesis of RNA consistent with Hadean natural history.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. The Origin of the Feedstock Molecules for Life on the Hadean Earth.Angewandte Chemie (International ed. in English) · 2025
    Article
  5. Rethinking nucleic acids from their origins to their applications.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  6. On the Origin of Sugar Handedness: Facts, Hypotheses and Missing Links-A Review.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2022
    Review
  7. Article
  8. Carbon dioxide photoreduction in prebiotic environments.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2022
    Review
  9. Depleted carbon isotope compositions observed at Gale crater, Mars.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  10. Article
  11. Article
  12. Prebiotic Chemistry that Could NotLife (Basel, Switzerland) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

J Kawai1 Foundation for Applied Molecular Evolution, Alachua, Florida, USA.
D Chris McLendon1 Foundation for Applied Molecular Evolution, Alachua, Florida, USA.
H-J Kim3 Firebird Biomolecular Sciences LLC, Alachua, Florida, USA.
S A Benner1 Foundation for Applied Molecular Evolution, Alachua, Florida, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While formaldehyde (HCHO) was likely generated in Earth's prebiotic atmosphere by ultraviolet light, electrical discharge, and/or volcano-created lightning, HCHO could not have accumulated in substantial amounts in prebiotic environments, including those needed for prebiotic processes that generate nucleosidic carbohydrates. HCHO at high concentrations in alkaline solutions self-reacts in the Cannizzaro reaction to give methanol and formate, neither having prebiotic value. Here, we explore the possibility that volcanic sulfur dioxide (SO

Indexed as

Origin of LifeVolcanic EruptionsCarbohydratesCarbon-13 Magnetic Resonance SpectroscopyDihydroxyacetoneFormaldehydeMesylatesMineralsProton Magnetic Resonance SpectroscopySolubilitySulfitesSulfur DioxideCarbohydratesDihydroxyacetoneFormaldehydeformaldehyde bisulfiteMesylatesMineralsSulfitesSulfur DioxideBorateCannizzaro reactionFormaldehydeHydroxymethanesulfonateOrganic mineralsOrigins of lifePrebiotic chemistry.Sulfur dioxide

Identifiers

PMID30615473
PMCPMC6459274

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.