ArticleJournal of medicinal chemistry2019
Substrate-Specific Inhibition Constants for Phospholipase A
Article in Journal of medicinal chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 25 citations in OpenAlex.
- Specificity mechanism of Group VIA calcium-independent phospholipase ABiochimica et biophysica acta. Molecular and cell biology of lipids · 2025Article
- A Lipidomic Approach to Studying the Downregulation of Free Fatty Acids by Cytosolic Phospholipase ABiomolecules · 2025Article
- The mechanism of allosteric regulation of calcium-independent phospholipase AProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Differentiating human phospholipase ABiochimica et biophysica acta. Molecular and cell biology of lipids · 2024Article
- Multiplatform Metabolomics Characterization Reveals Novel Metabolites and Phospholipid Compositional Rules ofInternational journal of molecular sciences · 2023Article
- Membrane Association Allosterically Regulates Phospholipase AAccounts of chemical research · 2022Article
- Outtakes from My Journey through the World of LIPID MAPS.Molecules (Basel, Switzerland) · 2022Article
- Predicting target-ligand interactions with graph convolutional networks for interpretable pharmaceutical discovery.Scientific reports · 2022Article
- Allosteric regulation by membranes and hydrophobic subsites in phospholipase AThe Journal of biological chemistry · 2022Review
- Article
- Lipoprotein-associated phospholipase AProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Serum metabolomic characterization of PLA2G6-associated dystonia-parkinsonism: A case-control biomarker study.Frontiers in neuroscience · 2022Article
- The Impact of the CaBiomolecules · 2021Review
- Omega-3 versus Omega-6 fatty acid availability is controlled by hydrophobic site geometries of phospholipase AJournal of lipid research · 2021Article
- Lipidomics-based assays coupled with computational approaches can identify novel phospholipase AAdvances in biological regulation · 2020Article
- 2-Oxoester Phospholipase ABiomolecules · 2020Article
- β-Lactones: A Novel Class of CaJournal of medicinal chemistry · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Assaying lipolytic enzymes is extremely challenging because they act on water-insoluble lipid substrates, which are normally components of micelles, vesicles, and cellular membranes. We extended a new lipidomics-based liquid chromatographic-mass spectrometric assay for phospholipases A
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.