ArticleNeuro-oncology2019
Body mass index, comorbidities, and hormonal factors in relation to meningioma in an ethnically diverse population: the Multiethnic Cohort.
Article in Neuro-oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Hormone therapy and the risk of central nervous system tumors in women: a systematic review and meta-analysis.Journal of neuro-oncology · 2026Pooled it
- Association between anthropometric factors and meningioma risk: A systematic review and meta-analysis.PloS one · 2025Pooled it
- Exogenous Hormones and Their Clinical Implications for the Development and Growth of Meningioma Tumours.Journal of clinical medicine · 2026Review
- Contraceptive Progestogens and Incident Meningioma.JAMA network open · 2026Article
- Associations of surgical menopause and hormone replacement therapy with meningioma development.Journal of neuro-oncology · 2026Article
- Hormonal contraceptives and the risk of meningioma: A Swedish register-based case-control study.Neuro-oncology · 2026Article
- Oral contraceptives with progestogens desogestrel or levonorgestrel and risk of intracranial meningioma: national case-control study.BMJ (Clinical research ed.) · 2025Article
- Association of thyroid disease and intracranial meningiomas: a retrospective analysis with external validation.Frontiers in oncology · 2025Article
- Paradoxical evolution of spheno-orbital meningioma after cessation of progestin treatment.Surgical neurology international · 2025Article
- Differences in tumor size, clinical, demographic, and socioeconomic profiles of central nervous system tumors among a racially diverse cohort: A retrospective case-control study.Surgical neurology international · 2024Article
- Life-style and metabolic factors do not affect risk for glioma: a prospective population-based study (The Cohort of Norway).Frontiers in oncology · 2024Article
- Lifestyle and metabolic factors affect risk for meningioma in women: a prospective population-based study (The Cohort of Norway).Frontiers in oncology · 2024Article
- Meningioma in the elderly.Neuro-oncology advances · 2023Article
- Meningioma and Other Meningeal Tumors.Advances in experimental medicine and biology · 2023Article
- The causal relationship between genetically determined telomere length and meningiomas risk.Frontiers in neurology · 2023Article
- Optimal annual body mass index change for preventing spontaneous preterm birth in a subsequent pregnancy.Scientific reports · 2022Article
- Annual Body Mass Index Gain and Risk of Gestational Diabetes Mellitus in a Subsequent Pregnancy.Frontiers in endocrinology · 2022Article
- Mitochondrial DNA sequence variation and risk of meningioma.Journal of neuro-oncology · 2021Article
- Annual body mass index gain and risk of hypertensive disorders of pregnancy in a subsequent pregnancy.Scientific reports · 2021Article
- A decreased risk of meningioma in women smokers was only observed in American studies rather than studies conducted in other countries: a systematic review and meta-analysis.Chinese neurosurgical journal · 2021Article
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7 authors.
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Abstract
backgroundMeningioma is the most common intracranial tumor in the US and its etiology remains poorly understood. Meningioma has been predominantly studied among white populations. The aim of this study was to evaluate the associations of anthropometric, comorbidity, and hormonal factors with meningioma in an ethnically diverse population.
methodsA nested case-control analysis was performed within the Multiethnic Cohort (MEC). Meningioma cases were identified via linkage with Medicare and the California Office of Statewide Health Planning and Development Hospital Discharge data and were matched to up to 10 controls. Anthropometric, comorbidities, physical activity level, and hormonal factors at baseline based on questionnaires were evaluated for association with meningioma.
resultsA total of 894 cases and 8918 matched controls were included in this study. Increasing body mass index (BMI) (P-trend = 0.041) and weight increases since age 21 (P-trend = 0.0052) were positively associated with meningioma. Hormonal factors including oral contraceptive use (odds ratio [OR]: 1.24; 95% CI: 1.01-1.51) and estrogen hormonal therapy use (per 5 years, OR: 1.07; 95% CI: 1.01-1.15) were associated with meningioma risk. Hypertension was positively associated with meningioma (OR: 1.26; 95% CI: 1.09-1.47), with individuals who reported a history of both hypertension and diabetes showing a stronger association (OR: 1.54; 95% CI: 1.17-2.03). The tests for heterogeneity across race/ethnicity were not statistically significant (P heterogeneity ≥ 0.17); however, the association of BMI with meningioma was mainly observed in Japanese Americans (P-trend = 0.0036) and hypertension in Japanese Americans (OR: 1.63; 95% CI: 1.17-2.27) and Native Hawaiians (OR: 1.86; 95% CI: 1.02-3.40).
conclusionObesity, hormonal factors, and hypertension were associated with meningioma in an ethnically diverse population.
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