ArticleAdvances in nutrition (Bethesda, Md.)2019
Perspective: The Dietary Inflammatory Index (DII)-Lessons Learned, Improvements Made, and Future Directions.
Article in Advances in nutrition (Bethesda, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 342 papers, 10 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of an Anti-Inflammatory Diet on Weight Loss, Body Composition, Cardiometabolic Risk Factors and Immune System Response in Younger Adults
Randomized Controlled Clinical Trial on the Anti-inflammatory Effect of a Sustainable Dietary Strategy in Adults With Obesity
Who cites it
342 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- Association of priori dietary patterns with metabolic syndrome and its components: a systematic review and meta-analysis.Frontiers in nutrition · 2026Pooled it
- High dietary inflammatory index is associated with an increased risk of overweight and obesity in adults: a meta-analysis of observational studies.Frontiers in nutrition · 2026Pooled it
- Does adopting a healthy diet improve periodontal parameters in patients susceptible to periodontal disease? A systematic review.Evidence-based dentistry · 2025Pooled it
- Dietary inflammatory index and the risk of esophageal cancer: a systematic review and meta-analysis.BMC cancer · 2025Pooled it
- Dietary inflammatory potential and the risk of cognitive impairment: A meta-analysis of prospective cohort studies.The journal of nutrition, health & aging · 2025Pooled it
- Pooled it
- Nonlinear dose-response relationship between dietary inflammatory index and risk of depression: a systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Dietary inflammatory index (DII) and sleep quality, duration, and timing: A systematic review.Sleep medicine reviews · 2024Pooled it
- What is the link between the dietary inflammatory index and the gut microbiome? A systematic review.European journal of nutrition · 2024Pooled it
- Dietary inflammatory index and the risks of non-alcoholic fatty liver disease: a systematic review and meta-analysis.Frontiers in nutrition · 2024Pooled it
- Dietary Inflammatory Index and Cardiovascular Disease Risk in Australian Adults: A Secondary Analysis of the OLIVAUS Trial.Nutrients · 2026Trial
- Comparison of mediterranean and healthy eating guideline interventions on the dietary inflammatory index in rheumatoid arthritis: results from a dietary randomised controlled intervention trial.European journal of nutrition · 2026Trial
- Maternal diet and gestational diabetes mellitus modestly influence children's growth during their first 24 months.Journal of pediatric gastroenterology and nutrition · 2025Trial
- The effects of the Multicultural Healthy Diet on cognitive decline and Alzheimer's disease risk: a phase II randomized controlled trial in middle-aged adults.The American journal of clinical nutrition · 2025Trial
- Trial
- Similar changes in diet quality indices, but not nutrients, among African American participants randomized to follow one of the three dietary patterns of the US Dietary Guidelines: A secondary analysis.Nutrition research (New York, N.Y.) · 2024Trial
- Association Between the Dietary Inflammatory Index and Cardiorenal Anemia Syndrome: Evidence From NHANES and Related-Phenotype Exploration in KNHANES.Food science & nutrition · 2026Article
- Parkinson's Disease: Pathophysiology, Treatment Strategies, Wellness Approaches, and Obstacles/Paths Forward.NeuroSci · 2026Review
- Dietary Inflammation, Gut Mycobiota, and Microbial Cross-Kingdom Associations with Cardiovascular Health in Older Adults.Metabolites · 2026Article
- Review
282 more citing papers are in PubMed but not listed here.
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5 authors.
Funding
Abstract
The literature on the role of inflammation in health has grown exponentially over the past several decades. Paralleling this growth has been an equally intense focus on the role of diet in modulating inflammation, with a doubling in the size of the literature approximately every 4 y. The Dietary Inflammatory Index (DII) was developed to provide a quantitative means for assessing the role of diet in relation to health outcomes ranging from blood concentrations of inflammatory cytokines to chronic diseases. Based on literature from a variety of different study designs ranging from cell culture to observational and experimental studies in humans, the DII was designed to be universally applicable across all human studies with adequate dietary assessment. Over the past 4 y, the DII has been used in >200 studies and forms the basis for 12 meta-analyses. In the process of conducting this work, lessons were learned with regard to methodologic issues related to total energy and nutrient intake and energy and nutrient densities. Accordingly, refinements to the original algorithm have been made. In this article we discuss these improvements and observations that we made with regard to misuse and misinterpretation of the DII and provide suggestions for future developments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.