Evidence map›Paper›PMID 30614787›Full record

ArticleeLife2019

Crystal structure of a natural light-gated anion channelrhodopsin.

Hai Li, Chia-Ying Huang, Elena G Govorunova, Christopher T Schafer, Oleg A Sineshchekov, Meitian Wang, Lei Zheng, John L Spudich

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Blue-shifted ancyromonad channelrhodopsins for multiplex optogenetics.bioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Potassium-selective channelrhodopsins.Biophysics and physicobiology · 2023
    Article
  17. Article
  18. Crystallization of Microbial Rhodopsins.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  19. Microbial Rhodopsins.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Hai LiDepartment of Biochemistry and Molecular Biology, Center for Membrane Biology, University of Texas Health Science Center - McGovern Medical School, Houston, United States.ORCID 0000-0002-3969-6709
Chia-Ying HuangSwiss Light Source, Paul Scherrer Institute, Villigen, Switzerland.ORCID 0000-0002-7676-0239
Elena G GovorunovaDepartment of Biochemistry and Molecular Biology, Center for Membrane Biology, University of Texas Health Science Center - McGovern Medical School, Houston, United States.
Christopher T SchaferDepartment of Biochemistry and Molecular Biology, Center for Membrane Biology, University of Texas Health Science Center - McGovern Medical School, Houston, United States.
Oleg A SineshchekovDepartment of Biochemistry and Molecular Biology, Center for Membrane Biology, University of Texas Health Science Center - McGovern Medical School, Houston, United States.
Meitian WangSwiss Light Source, Paul Scherrer Institute, Villigen, Switzerland.
Lei ZhengDepartment of Biochemistry and Molecular Biology, Center for Membrane Biology, University of Texas Health Science Center - McGovern Medical School, Houston, United States.ORCID 0000-0001-7789-5234
John L SpudichDepartment of Biochemistry and Molecular Biology, Center for Membrane Biology, University of Texas Health Science Center - McGovern Medical School, Houston, United States.ORCID 0000-0003-4167-8590
The University of Texas Health Science Center at Houston · USPaul Scherrer Institute · CH

Funding

Structure/Function of Microbial Sensory RhodopsinsR01GM027750 · NIGMS · YESHIVA UNIVERSITY · PI SPUDICH, JOHN LEE · 1985 to 2020
$6.6M
Anion channelrhodopsin-based viral tools to manipulate brain networks in behaving animalsU01MH109146 · NIMH · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI DRAGOI, VALENTIN, JANZ, ROGER · 2015 to 2017
$3.0M
American Heart Association 18TPA34230046H2020 Marie Skłodowska-Curie Actions 701647Marie-Skłodowska-Curie 701647NIGMS NIH HHS R01 GM027750NIH HHS R01GM027750NIH HHS U01MH109146NIMH NIH HHS U01 MH109146Welch Foundation AU-0009
6 · The paper itself

Abstract

The anion channelrhodopsin

Indexed as

AnionsChannelrhodopsinsCryptophytaCrystallography, X-RayIon Channel GatingIon TransportOptogeneticsRetinoidsSchiff BasesAnionsChannelrhodopsinsRetinoidsretinylidene chromophoreSchiff Basesanion channelrhodopsinbiochemistrychemical biologyGuillardia thetamolecular biophysicsoptogeneticsstructural biology

Identifiers

PMID30614787
PMCPMC6336409
OpenAlexW2889267696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.