Evidence map›Paper›PMID 30614779›Full record

Trial reportNutritional neuroscience2020

Autonomic activity and its relationship with the endogenous cardiotonic steroid marinobufagenin: the African-PREDICT study.

Michél Strauss, Wayne Smith, Wen Wei, Olga V Fedorova, Aletta E Schutte

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in Nutritional neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Day and night heart rate variability using 24-h ECG recordings: a systematic review with meta-analysis using a gender lens.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2023
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. The NaCurrent hypertension reports · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Michél StraussHypertension in Africa Research Team (HART), North-West University, Potchefstroom, South Africa.
Wayne SmithHypertension in Africa Research Team (HART), North-West University, Potchefstroom, South Africa.ORCID https://orcid.org/0000-0002-7101-7331
Wen WeiLaboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, MD, USA.
Olga V FedorovaLaboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, MD, USA.
Aletta E SchutteHypertension in Africa Research Team (HART), North-West University, Potchefstroom, South Africa.ORCID https://orcid.org/0000-0001-9217-4937
North-West University · ZANational Institute on Aging · US

Funding

Exploring the involvement of Na pump inhibitor marinobufagenin in the interactions between age-associated vascular and neurodegenerative processes in cognitive impairment and Alzheimer's diseaseZIAAG000846 · NIA · NATIONAL INSTITUTE ON AGING · PI FEDOROVA, OLGA V · 2016 to 2025
$17.7M
Sodium pump ligands in blood pressure regulation and profibrotic signaling in hypertension, chronic kidney disease and aging in males and femalesZIAAG000609 · NIA · NATIONAL INSTITUTE ON AGING · PI FEDOROVA, OLGA V · 2009 to 2025
$17.3M
Marinobufagenin as a therapeutic targetZIAAG000869 · NIA · NATIONAL INSTITUTE ON AGING · PI LAKATTA, EDWARD · 2009 to 2025
$14.8M
Intramural NIH HHS ZIA AG000846Medical Research Council MC_PC_16095
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAldosteroneAutonomic Nervous SystemBlood PressureBufanolidesCardiac GlycosidesCross-Sectional StudiesElectrocardiographyFemaleHeart RateHumansMaleYoung AdultAldosteroneBufanolidesCardiac GlycosidesmarinobufageninAutonomic activityhumanmarinobufageninsalt intakewomen

Identifiers

PMID30614779
PMCPMC7574629
OpenAlexW2910203123

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.