Evidence map›Paper›PMID 30614639›Full record

ArticleESC heart failure2019

Design and rationale of haemodynamic guidance with CardioMEMS in patients with a left ventricular assist device: the HEMO-VAD pilot study.

Jesse F Veenis, Olivier C Manintveld, Alina A Constantinescu, Kadir Caliskan, Ozcan Birim, Jos A Bekkers, Nicolas M van Mieghem, Corstiaan A den Uil, Eric Boersma, Mattie J Lenzen and 4 more

Open access · goldAbstract read
In one paragraph

Article in ESC heart failure, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 35 citations in OpenAlex.

  1. Materials Advances in Devices for Heart Disease Interventions.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  2. Hemodynamic Monitoring of Pediatric Patients With Heart Failure and Pulmonary Hypertension Using CardioMEMS.Journal of the Society for Cardiovascular Angiography & Interventions · 2024
    Article
  3. Review
  4. Article
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  6. Article
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  11. Article
  12. Article
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  14. Telemonitoring in Heart Failure Management.Cardiac failure review · 2020
    Review
  15. Review
  16. Review
  17. CardioMEMS: where we are and where can we go?Annals of translational medicine · 2019
    Review
  18. Article
  19. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Jesse F VeenisDepartment of Cardiology, Erasmus MC Thoraxcenter, Rotterdam, The Netherlands.ORCID 0000-0001-7234-8266
Olivier C ManintveldDepartment of Cardiology, Erasmus MC Thoraxcenter, Rotterdam, The Netherlands.
Alina A ConstantinescuDepartment of Cardiology, Erasmus MC Thoraxcenter, Rotterdam, The Netherlands.
Kadir CaliskanDepartment of Cardiology, Erasmus MC Thoraxcenter, Rotterdam, The Netherlands.
Ozcan BirimDepartment of Cardiothoracic Surgery, Erasmus MC Thoraxcenter, Rotterdam, The Netherlands.
Jos A BekkersDepartment of Cardiothoracic Surgery, Erasmus MC Thoraxcenter, Rotterdam, The Netherlands.
Nicolas M van MieghemDepartment of Cardiology, Erasmus MC Thoraxcenter, Rotterdam, The Netherlands.
Corstiaan A den UilDepartment of Cardiology, Erasmus MC Thoraxcenter, Rotterdam, The Netherlands.
Eric BoersmaDepartment of Cardiology, Erasmus MC Thoraxcenter, Rotterdam, The Netherlands.
Mattie J LenzenDepartment of Cardiology, Erasmus MC Thoraxcenter, Rotterdam, The Netherlands.
Felix ZijlstraDepartment of Cardiology, Erasmus MC Thoraxcenter, Rotterdam, The Netherlands.
William T AbrahamDivision of Cardiovascular Medicine, The Ohio State University, Colombus, OH, USA.
Philip B AdamsonDivision of Cardiology, Oklahoma Foundation for Cardiovascular Research, Oklahoma City, OK, USA.
Jasper J BrugtsDepartment of Cardiology, Erasmus MC Thoraxcenter, Rotterdam, The Netherlands.
Erasmus MC · NLOklahoma Medical Research Foundation · USThe Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsWe aim to study the feasibility and clinical value of pulmonary artery pressure monitoring with the CardioMEMS™ device in order to optimize and guide treatment in patients with a HeartMate 3 left ventricular assist device (LVAD). METHODS AND

resultsIn this single-centre, prospective pilot study, we will include 10 consecutive patients with New York Heart Association Class IIIb or IV with Interagency Registry for Mechanically Assisted Circulatory Support Classes 2-5 scheduled for implantation of a HeartMate 3 LVAD. Prior to LVAD implantation, patients will receive a CardioMEMS sensor, for daily pulmonary pressure readings. The haemodynamic information provided by the CardioMEMS will be used to improve haemodynamic status prior to LVAD surgery and optimize the timing of LVAD implantation. Post-LVAD implantation, the haemodynamic changes will be assessed for additive value in detecting potential complications in an earlier stage (bleeding and tamponade). During the outpatient clinic phase, we will assess whether the haemodynamic feedback can optimize pump settings, detect potential complications, and further tailor the clinical management of these patients.

conclusionsThe HEMO-VAD study is the first prospective pilot study to explore the safety and feasibility of using CardioMEMS for optimization of LVAD therapy with additional (remote) haemodynamic information.

Indexed as

Heart-Assist DevicesQuality of LifeRegistriesFeasibility StudiesHeart FailureHemodynamic MonitoringHemodynamicsHumansPilot ProjectsProspective StudiesCardioMEMSHeart failureHeartMate 3Implantable haemodynamic monitoringLVADTelemonitoring

Identifiers

PMID30614639
PMCPMC6351888
OpenAlexW2911134780

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.