Evidence map›Paper›PMID 30614621›Full record

ArticleJournal of biomedical materials research. Part B, Applied biomaterials2019

Efficacy of a synthetic calcium phosphate with submicron surface topography as autograft extender in lapine posterolateral spinal fusion.

Lukas A van Dijk, Davide Barbieri, Florence Barrère-de Groot, Huipin Yuan, Rema Oliver, Chris Christou, William R Walsh, Joost D de Bruijn

Abstract read
In one paragraph

Article in Journal of biomedical materials research. Part B, Applied biomaterials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Ceramic bone graft substitute vs autograft in XLIF: a prospective randomized single-center evaluation of radiographic and clinical outcomes.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lukas A van DijkKuros Biosciences BV, Bilthoven, the Netherlands.ORCID 0000-0002-2018-4041
Davide BarbieriKuros Biosciences BV, Bilthoven, the Netherlands.
Florence Barrère-de GrootKuros Biosciences BV, Bilthoven, the Netherlands.
Huipin YuanKuros Biosciences BV, Bilthoven, the Netherlands.ORCID 0000-0003-3353-7122
Rema OliverSurgical and Orthopedic Research Laboratories, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0002-2381-7326
Chris ChristouSurgical and Orthopedic Research Laboratories, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0003-3231-0356
William R WalshSurgical and Orthopedic Research Laboratories, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0002-5023-6148
Joost D de BruijnKuros Biosciences BV, Bilthoven, the Netherlands.ORCID 0000-0003-0367-3633

Funding

European Union's Horizon 2020 research and innovation program 674282
6 · The paper itself

Abstract

Posterolateral spinal fusion (PLF) is a common procedure in orthopedic surgery that is performed to fuse adjacent vertebrae to reduce symptoms related to spinal conditions. In the current study, a novel synthetic calcium phosphate with submicron surface topography was evaluated as an autograft extender in a validated rabbit model of PLF. Fifty-nine skeletally mature New Zealand white rabbits were divided into three groups and underwent single-level intertransverse process PLF at L4-5 using (1) autologous bone graft (ABG) alone or in a 1:1 combination with (2) calcium phosphate granules (ABG/BCP

Indexed as

Bone SubstitutesBone TransplantationCalcium PhosphatesSpinal FusionAnimalsAutograftsOsteogenesisRabbitsSurface PropertiesBone Substitutescalcium phosphateCalcium Phosphatescalcium phosphateposterolateral spinal fusionrabbitsubmicron surface topography

Identifiers

PMID30614621
PMCPMC6690075

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.