Evidence map›Paper›PMID 30614096›Full record

ArticleAddiction (Abingdon, England)2019

Measurement-based care using DSM-5 for opioid use disorder: can we make opioid medication treatment more effective?

John Marsden, Betty Tai, Robert Ali, Lian Hu, A John Rush, Nora Volkow

Abstract read
In one paragraph

Article in Addiction (Abingdon, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

John MarsdenAddictions Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.ORCID 0000-0002-1307-2498
Betty TaiNational Institute on Drug Abuse, National Institutes of Health, Rockville, MD, USA.
Robert AliDiscipline of Pharmacology, School of Medicine, The University of Adelaide, South Australia.
Lian HuNational Institute on Drug Abuse, National Institutes of Health, Rockville, MD, USA.
A John RushDuke-National University of Singapore, Singapore.
Nora VolkowNational Institute on Drug Abuse, National Institutes of Health, Rockville, MD, USA.

Funding

Neurobiology of Substance Abuse and AddictionZIAAA000550 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI VOLKOW, NORA D. · 2009 to 2025
$115.1M
6 · The paper itself

Abstract

context and purposeMeasurement-based care (MBC) is an evidence-based health-care practice in which indicators of disease are tracked to inform clinical actions, provide feedback to patients and improve outcomes. The current opioid crisis in multiple countries provides a pressing rationale for adopting a basic MBC approach for opioid use disorder (OUD) using DSM-5 to increase treatment retention and effectiveness. PROPOSAL: To stimulate debate, we propose a basic MBC approach using the 11 symptoms of OUD (DSM-5) to inform the delivery of medications for opioid use disorder (MOUD; including methadone, buprenorphine and naltrexone) and their evaluation in office-based primary care and specialist clinics. Key features of a basic MBC approach for OUD using DSM-5 are described, with an illustration of how clinical actions are guided and outcomes communicated. For core treatment tasks, we propose that craving and drug use response to MOUD should be assessed after 2 weeks, and OUD remission status should be evaluated at 3, 6 and 12 months (and exit from MOUD treatment) and beyond. Each of the 11 DSM-5 symptoms of OUD should be discussed with the patient to develop a case formulation and guide selection of adjunctive psychological interventions, supplemented with information on substance use, and optionally extended with information from other clinical instruments. A patient-reported outcome measure should be recorded and discussed at each remission assessment.

conclusionsMBC can be used to tailor and adapt MOUD treatment to increase engagement, retention and effectiveness. MBC practice principles can help promote patient-centred care in OUD, personalized addiction therapeutics and facilitate communication of outcomes.

Indexed as

Diagnostic and Statistical Manual of Mental DisordersPatient Reported Outcome MeasuresAnalgesics, OpioidBuprenorphineEvidence-Based MedicineHumansInternational Classification of DiseasesMethadoneNaltrexoneNarcotic AntagonistsOpioid-Related DisordersRemission InductionAnalgesics, OpioidBuprenorphineMethadoneNaltrexoneNarcotic AntagonistsDSM-5measurement-based care (MBC)medications for opioid use disorder (MOUD)opioid use disorder (OUD)patient reported outcome (PRO)psychological intervention

Identifiers

PMID30614096
PMCPMC6766896

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.