Evidence map›Paper›PMID 30613926›Full record

ArticleJournal of gastrointestinal cancer2020

Influence of Treatment Caused Impairments on Anxiety and Depression in Patients with Cancer of the Esophagus or the Esophagogastric Junction.

Thomas Kiefer, Dorothea Krahl, Carsten Hirt, Heinz Völler, Lorenz Völkel, Georg Daeschlein

Abstract read
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In one paragraph

Article in Journal of gastrointestinal cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Thomas KieferKlinik am See, Seebad 84, 15562, Rüdersdorf bei, Berlin, Germany. Thomas.Kiefer-Trendelenburg@klinikamsee.com.ORCID http://orcid.org/0000-0002-7283-4990
Dorothea KrahlKlinik am See, Seebad 84, 15562, Rüdersdorf bei, Berlin, Germany.
Carsten HirtDepartment of Internal Medicine C, Hematology/Oncology, University of Greifswald, Greifswald, Germany.
Heinz VöllerKlinik am See, Seebad 84, 15562, Rüdersdorf bei, Berlin, Germany.
Lorenz VölkelKlinik am See, Seebad 84, 15562, Rüdersdorf bei, Berlin, Germany.
Georg DaeschleinDepartment of Dermatology, University Medicine Greifswald, Greifswald, Germany.
Trend Micro (Japan) · JPUniversität Greifswald · DEUniversitätsmedizin Greifswald · DEUniversity of Potsdam · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAfter therapy of cancer of the esophagus or the esophagogastric junction, patients often suffer from anxiety and depression. Some risk factors for elevated anxiety and depression are reported, but the influence of steatorrhea, the frequency of which has only recently been reported, has not yet been investigated.

methodUsing the Hospital Anxiety and Depression Scale (HADS), we analyzed the correlation of anxiety and depression with steatorrhea, appetite, and weight loss in 72 patients with cancer of the esophagus or of the esophagogastric junction, who were treated at our rehabilitation clinic between January 2011 and December 2014. In addition, effectiveness of psychological interviews was analyzed.

resultsWe have evaluable anxiety questionnaires from 51 patients showing a median anxiety value of 5 (range 0-13). As for the depression, results from evaluable questionnaires of 54 patients also showed a median value of 5 (range 0-15). Increased anxiety and depression values (> 7) were observed in 25.4% and 37.0% of the patients respectively. Patients who were admitted with steatorrhea for rehabilitation showed a statistically higher anxiety value (median 6.3 vs. 4.7, p < 0.05), reduced appetite, and a weight loss above 15 kg depicting a correlation to anxiety and depression. Psychological conversations helped lowering the depression but had no influence on anxiety.

conclusionsImpairments after cancer treatment, such as steatorrhea, appetite loss, and weight loss, should be interpreted as an alarm signal and should necessitate screening for increased anxiety and depression. Psychological therapy can help improving the extent of the depression.

Indexed as

AdultAgedAged, 80 and overAnxietyDepressionEsophageal NeoplasmsEsophagogastric JunctionFemaleHumansMaleMiddle AgedRetrospective StudiesAnxietyDepressionEsophagus carcinomaExocrine pancreas insufficiencyRehabilitationSteatorrhea

Identifiers

PMID30613926
OpenAlexW2907983909

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.