Evidence map›Paper›PMID 30613921›Full record

ArticlePathology oncology research : POR2020

Selective Inhibition of HIF1α Expression by ZnSO

Z Burián, A Ladányi, T Barbai, V Piurkó, T Garay, E Rásó, József Tímár

Abstract read
PubMed Publisher
In one paragraph

Article in Pathology oncology research : POR, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Z BuriánNational Institute of Oncology, Budapest, Hungary.
A LadányiNational Institute of Oncology, Budapest, Hungary.
T Barbai2nd Department of Pathology, Semmelweis University, Üllői út 93., Budapest, H-1091, Hungary.
V Piurkó2nd Department of Pathology, Semmelweis University, Üllői út 93., Budapest, H-1091, Hungary.
T Garay2nd Department of Pathology, Semmelweis University, Üllői út 93., Budapest, H-1091, Hungary.
E Rásó2nd Department of Pathology, Semmelweis University, Üllői út 93., Budapest, H-1091, Hungary.
József Tímár2nd Department of Pathology, Semmelweis University, Üllői út 93., Budapest, H-1091, Hungary. jtimar@gmail.com.ORCID http://orcid.org/0000-0001-9183-0859
Semmelweis University · HUNational Institute of Oncology · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zinc as an essential trace metal is a ubiquitous component of various molecules of the cell. Studies indicated that it may modulate functions of various cancer cell types, and can even inhibit metastasis formation in experimental models. In melanoma, zinc was shown to affect melanin production and to induce apoptosis. Using human melanoma cell lines, we have tested the effects of ZnSO

Indexed as

AnimalsAntineoplastic AgentsApoptosisCell MovementCell ProliferationHumansHypoxia-Inducible Factor 1, alpha SubunitMelanomaMiceMice, SCIDXenograft Model Antitumor AssaysZinc SulfateAntineoplastic AgentsHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitZinc SulfateHIF1αHuman melanomaMetastasis inhibitionZnSO4

Identifiers

PMID30613921
OpenAlexW2907341022

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.