Evidence map›Paper›PMID 30613762›Full record

ArticleBio-protocol2018

Mosaic Labeling and 3-Dimensional Morphological Analysis of Single Cells in the Zebrafish Left-right Organizer.

Agnik Dasgupta, Andrew E Jacob, Jeffrey D Amack

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bio-protocol, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Agnik DasguptaDepartment of Cell and Developmental Biology, State University of New York Upstate Medical University, Syracuse, NY, USA.
Andrew E JacobDepartment of Cell and Developmental Biology, State University of New York Upstate Medical University, Syracuse, NY, USA.
Jeffrey D AmackDepartment of Cell and Developmental Biology, State University of New York Upstate Medical University, Syracuse, NY, USA.

Funding

Regulation of Ciliated Cells that Control Cardiac LateralityR01HL095690 · NHLBI · UPSTATE MEDICAL UNIVERSITY · PI AMACK, JEFFREY D · 2009 to 2014
$1.7M
Quantitative Modeling of Cell Shape Changes During OrganogenesisR01GM117598 · NIGMS · SYRACUSE UNIVERSITY · PI MANNING, MARY ELIZABETH LISA · 2015 to 2018
$1.0M
NHLBI NIH HHS R01 HL095690NIGMS NIH HHS R01 GM117598
6 · The paper itself

Abstract

A transient epithelial structure called the left-right organizer (LRO) establishes left-right asymmetry in vertebrate embryos. Developmental defects that alter LRO formation result in left-right patterning errors that often lead to congenital heart malformations. However, little is known about mechanisms that regulate individual cell behaviors during LRO formation. To address this, we developed a Cre-

Indexed as

3D reconstructionsDorsal forerunner cellsKupffer’s vesicleLeft-right organizerMorphometric analysisMosaic labelingSingle cellZebrafish embryo

Identifiers

PMID30613762
PMCPMC6319891

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.