ArticleJournal of family medicine and primary care
Decreasing trend of seroprevalence of leptospirosis at All India Institute of Medical Sciences New Delhi: 2014-2018.
Article in Journal of family medicine and primary care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Clinico-Epidemiological Profile of Leptospirosis Among Patients Attending a Tertiary Care Center in Rajasthan.Cureus · 2026Article
- Clinical characteristics and seroprevalence of leptospirosis in patients with acute undifferentiated fever: A cross-sectional study.Journal of family medicine and primary care · 2025Article
- In-House IgM Dot-Blot Assay for Serodiagnosis of Human Leptospirosis: Development, Standardisation, and Performance Evaluation.Microorganisms · 2025Article
- Challenging trends in clinical-epidemiology and sero-prevalence of leptospirosis among febrile patients.Bioinformation · 2025Article
- Epidemiological determinants of leptospirosis in rural and urban districts of Maharashtra, India.Journal of family medicine and primary care · 2021Article
- A case of neglected hepatorenal dysfunction during the COVID pandemic.Indian journal of medical microbiology · 2021Article
- Journey towards National Institute of One Health in India.The Indian journal of medical research · 2021Article
- Clinical profile, management and outcome of patients with leptospirosis during the times of COVID-19 pandemic: A prospective study from a tertiary care centre in South India.Le infezioni in medicina · 2021Article
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5 authors.
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Abstract
backgroundLeptospirosis is an important emerging public health problem in India. There is limited information regarding the seroprevalence of leptospirosis in population from northern states of India. This study reports result of a 4-year-retrospective sero-epidemiological survey of leptospirosis conducted in a teaching tertiary care hospital in New Delhi, India. The aim of our study was to explore seroprevalence and clinical pattern of disease occurrence in suspected cases of leptospirosis and to search for any co-existing infections in northern areas such as New Delhi, India.
methodsThe patients with clinically suspected leptospirosis who attended outpatient or admitted to the Departments of Medicine, Gastroenterology, Pediatrics and Neurology, etc. of our hospital were retrospectively analyzed. The qualitative determination of anti-leptospira-specific immunoglobulin (IgM) antibodies was carried out using commercially available enzyme-linked immunosorbent assay (ELISA) kit (Panbio Diagnostics, Brisbane, Australia).
resultsOf these 1545 patients, 6.47% (100/1545) were seropositive for anti-leptospira-specific immunoglobulin (IgM) antibodies. Using modified Faine's criteria, a diagnosis of presumptive and possible leptospirosis was made in 79/100 (79%) and 21/100 (21%) patients. Significant declining trend of seroprevalence rate of leptospirosis from 26.90% in 2000-2010 and 20% in 2011-2014 to 6.47% in 2014-2018 (
conclusionThere is a need to increase awareness among public and clinicians, however, more region/province-wise studies on seroprevalence of leptospirosis are required to improve our understanding of the actual burden.
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