Evidence map›Paper›PMID 30613466›Full record

ReviewJournal of kidney cancer and VHL2018

Clinical Syndromes and Genetic Screening Strategies of Pheochromocytoma and Paraganglioma.

Peihua Liu, Minghao Li, Xiao Guan, Anze Yu, Qiao Xiao, Cikui Wang, Yixi Hu, Feizhou Zhu, Hongling Yin, Xiaoping Yi and 1 more

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of kidney cancer and VHL, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Head and Neck Paragangliomas-A Genetic Overview.International journal of molecular sciences · 2020
    Review
  8. Article
  9. The role of CSDE1 in translational reprogramming and human diseases.Cell communication and signaling : CCS · 2020
    Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Peihua LiuDepartment of Urology, Xiangya Hospital, Central South University, Changsha, China.
Minghao LiDepartment of Urology, Xiangya Hospital, Central South University, Changsha, China.
Xiao GuanDepartment of Urology, Xiangya Hospital, Central South University, Changsha, China.
Anze YuDepartment of Urology, Xiangya Hospital, Central South University, Changsha, China.
Qiao XiaoDepartment of Urology, Xiangya Hospital, Central South University, Changsha, China.
Cikui WangDepartment of Urology, Xiangya Hospital, Central South University, Changsha, China.
Yixi HuDepartment of Urology, Xiangya Hospital, Central South University, Changsha, China.
Feizhou ZhuDepartment of Biochemistry and Molecular Biology, School of Life Sciences, Central South University, Changsha, China.
Hongling YinDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Xiaoping YiDepartment of Radiology, Xiangya Hospital, Central South University, Changsha, China.
Longfei LiuDepartment of Urology, Xiangya Hospital, Central South University, Changsha, China.
Central South University · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pheochromocytomas (PCCs) are rare neuroendocrine tumors that originate from chromaffin cells of the adrenal medulla, and paragangliomas (PGLs) are extra-adrenal pheochromocytomas. These can be mainly found in clinical syndromes including multiple endocrine neoplasia (MEN), von Hippel-Lindau (VHL) syndrome, neurofibromatosis-1 (NF-1) and familial paraganglioma (FPGL). PCCs and PGLs are thought to have the highest degree of heritability among human tumors, and it has been estimated that 60% of the patients have genetic abnormalities. This review provides an overview of the clinical syndrome and the genetic screening strategies of PCCs and PGLs. Comprehensive screening principles and strategies, along with specific screening based on clinical symptoms, biochemical tests and immunohistochemistry, are discussed.

Indexed as

multiple endocrine neoplasianeurofibromatosis-1paragangliomapheochromocytomavon Hippel–Lindau syndrome

Identifiers

PMID30613466
PMCPMC6308242
OpenAlexW2907482087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.