ArticleACS medicinal chemistry letters2018
Improving the Efficiency of the Drug Development by Expanding the Scope of the Role of Medicinal Chemists in Drug Discovery.
Article in ACS medicinal chemistry letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Antileishmanial Drug Discovery and Development: Time to Reset the Model?Microorganisms · 2021Review
- Synthesis, In Vitro Antioxidant Properties and Distribution of a New Cyanothiophene-Based Phenolic Compound in Olive Oil-In-Water Emulsions.Antioxidants (Basel, Switzerland) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Improvements in the efficiency of the drug discovery process are needed in order to deliver life-saving medications to patients in a more cost-effective manner. While there are many reasons that the efficiency of this process has not gotten better, this Viewpoint proposes that the lack of integration of the three major disciplines (discovery, development, and clinical trials) plays a significant role in the ongoing high rate of failure in clinical trials for innovative drugs. Several specific proposals are made that may help to provide more integration, so that the gears of the human-driven drug discovery machine may mesh better in the future.
Identifiers
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Registered trials
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