Evidence map›Paper›PMID 30613313›Full record

ArticleWorld journal of stem cells2018

Functional and molecular mechanism of intracellular pH regulation in human inducible pluripotent stem cells.

Shih-Chi Chao, Gwo-Jang Wu, Shu-Fu Huang, Niann-Tzyy Dai, Hsu-Kai Huang, Mei-Fang Chou, Yi-Ting Tsai, Shiao-Pieng Lee, Shih-Hurng Loh

Open access · hybridAbstract read
In one paragraph

Article in World journal of stem cells, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Automated high-content imaging in iPSC-derived neuronal progenitors.SLAS discovery : advancing life sciences R & D · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Shih-Chi ChaoGraduate Institute of Life Sciences, National Defense Medical Center, Taipei 11490, Taiwan.
Gwo-Jang WuDepartment of Obstetrics and Gynecology, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.
Shu-Fu HuangDepartment of Pharmacy Practice, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.
Niann-Tzyy DaiDivision of Plastic and Reconstructive Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.
Hsu-Kai HuangDivision of Chest Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.
Mei-Fang ChouDepartment of Pharmacy Practice, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.
Yi-Ting TsaiGraduate Institute of Medical Sciences, National Defense Medical Center, Taipei 11490, Taiwan.
Shiao-Pieng LeeDivision of Oral and Maxillofacial Surgery, Department of Dentistry, School of Dentistry, Tri-Service General Hospital and National Defense Medical Center, Taipei 11490, Taiwan.
Shih-Hurng LohGraduate Institute of Life Sciences, National Defense Medical Center, Taipei 11490, Taiwan.
National Defense Medical Center · TWTri-Service General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo establish a functional and molecular model of the intracellular pH (pH

methodshiPSCs (HPS0077) were kindly provided by Dr. Dai from the Tri-Service General Hospital (IRB No. B-106-09). Changes in the pH

resultsIn this study, our results indicated that (1) the steady-state pH

conclusionFor the first time, we established a functional and molecular model of a pH

Indexed as

BCECFCl-/HCO3- exchangerCl-/OH- exchangerHuman induced pluripotent stem cellsIntracellular buffering powerIntracellular pHMicrospectrofluorimetryNa+/HCO3- cotransporterNa+/H+ exchangerV-ATPase

Identifiers

PMID30613313
PMCPMC6306555
OpenAlexW2906345683

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.