Evidence map›Paper›PMID 30613286›Full record

ArticleTheranostics2018

Photoacoustic microscopy reveals the hemodynamic basis of sphingosine 1-phosphate-induced neuroprotection against ischemic stroke.

Rui Cao, Jun Li, Yugesh Kharel, Chenchu Zhang, Emily Morris, Webster L Santos, Kevin R Lynch, Zhiyi Zuo, Song Hu

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Homer1 ameliorates ischemic stroke by inhibiting necroptosis-induced neuronal damage and neuroinflammation.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Article
  8. Super-Low-Dose Functional and Molecular Photoacoustic Microscopy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Longitudinal cortex-wide monitoring of cerebral hemodynamics and oxygen metabolism in awake mice using multi-parametric photoacoustic microscopy.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
  18. Multi-scale optoacoustic molecular imaging of brain diseases.European journal of nuclear medicine and molecular imaging · 2021
    Review
  19. Hemodynamic and oxygen-metabolic responses of the awake mouse brain to hypercapnia revealed by multi-parametric photoacoustic microscopy.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Rui CaoDepartment of Biomedical Engineering, University of Virginia, Charlottesville, USA.
Jun LiDepartment of Anesthesiology, University of Virginia, Charlottesville, USA.
Yugesh KharelDepartment of Pharmacology, University of Virginia, Charlottesville, USA.
Chenchu ZhangDepartment of Biomedical Engineering, University of Virginia, Charlottesville, USA.
Emily MorrisDepartment of Chemistry and VT Center for Drug Discovery, Virginia Tech, Blacksburg, USA.
Webster L SantosDepartment of Chemistry and VT Center for Drug Discovery, Virginia Tech, Blacksburg, USA.
Kevin R LynchDepartment of Pharmacology, University of Virginia, Charlottesville, USA.
Zhiyi ZuoDepartment of Anesthesiology, University of Virginia, Charlottesville, USA.
Song HuDepartment of Biomedical Engineering, University of Virginia, Charlottesville, USA.
University of Virginia · USVirginia Tech · US

Funding

MD-PHAR Controlling sphingosine 1-phosphate synthesis and traffickingR01GM121075 · NIGMS · UNIVERSITY OF VIRGINIA · PI LYNCH, KEVIN R., SANTOS, WEBSTER L · 2016 to 2020
$2.1M
Photoacoustic Microscopy of the Awake Mouse BrainR01NS099261 · NINDS · WASHINGTON UNIVERSITY · PI HU, SONG · 2017 to 2021
$1.7M
NIGMS NIH HHS R01 GM121075NINDS NIH HHS R01 NS099261
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBrainBrain IschemiaEnzyme InhibitorsHemodynamicsHumansLysophospholipidsMaleMiceMicroscopyNeuroprotectionNeuroprotective AgentsOxygenPhosphotransferases (Alcohol Group Acceptor)Photoacoustic TechniquesSphingosineEnzyme InhibitorsLysophospholipidsNeuroprotective AgentsOxygenPhosphotransferases (Alcohol Group Acceptor)Sphingosinesphingosine 1-phosphateSphingosine KinaseHypoxiaIschemic stroke.NeuroprotectionPhotoacoustic microscopySphingosine 1-phosphate

Identifiers

PMID30613286
PMCPMC6299683
OpenAlexW2902132573

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.