Evidence map›Paper›PMID 30613284›Full record

ReviewTheranostics2018

The theranostic promise for Neuroendocrine Tumors in the late 2010s - Where do we stand, where do we go?

Rudolf A Werner, Alexander Weich, Malte Kircher, Lilja B Solnes, Mehrbod S Javadi, Takahiro Higuchi, Andreas K Buck, Martin G Pomper, Steven P Rowe, Constantin Lapa

Open access · goldAbstract readReview
In one paragraph

Review in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 78 citations in OpenAlex.

  1. Article
  2. Review
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  7. Review
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  9. Article
  10. Predicting [EJNMMI physics · 2023
    Article
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  13. Determinants of target absorbed dose in radionuclide therapy.Zeitschrift fur medizinische Physik · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Rudolf A WernerThe Russell H. Morgan Department of Radiology and Radiological Science, Division of Nuclear Medicine and Molecular Imaging, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Alexander WeichEuropean Neuroendocrine Tumor Society (ENETS) Center of Excellence (CoE), NET Zentrum, University Hospital Würzburg, Germany.
Malte KircherDepartment of Nuclear Medicine/Comprehensive Heart Failure Center, University Hospital Würzburg, Germany.
Lilja B SolnesThe Russell H. Morgan Department of Radiology and Radiological Science, Division of Nuclear Medicine and Molecular Imaging, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Mehrbod S JavadiThe Russell H. Morgan Department of Radiology and Radiological Science, Division of Nuclear Medicine and Molecular Imaging, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Takahiro HiguchiDepartment of Nuclear Medicine/Comprehensive Heart Failure Center, University Hospital Würzburg, Germany.
Andreas K BuckDepartment of Nuclear Medicine/Comprehensive Heart Failure Center, University Hospital Würzburg, Germany.
Martin G PomperThe Russell H. Morgan Department of Radiology and Radiological Science, Division of Nuclear Medicine and Molecular Imaging, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Steven P RoweThe Russell H. Morgan Department of Radiology and Radiological Science, Division of Nuclear Medicine and Molecular Imaging, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Constantin LapaDepartment of Nuclear Medicine/Comprehensive Heart Failure Center, University Hospital Würzburg, Germany.
Johns Hopkins University · USUniversitätsklinikum Würzburg · DEEuropean Neuroendocrine Tumor Society · DEJohns Hopkins Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

More than 25 years after the first peptide receptor radionuclide therapy (PRRT), the concept of somatostatin receptor (SSTR)-directed imaging and therapy for neuroendocrine tumors (NET) is seeing rapidly increasing use. To maximize the full potential of its theranostic promise, efforts in recent years have expanded recommendations in current guidelines and included the evaluation of novel theranostic radiotracers for imaging and treatment of NET. Moreover, the introduction of standardized reporting framework systems may harmonize PET reading, address pitfalls in interpreting SSTR-PET/CT scans and guide the treating physician in selecting PRRT candidates. Notably, the concept of PRRT has also been applied beyond oncology,

Indexed as

AnimalsHumansNeuroendocrine TumorsRadiopharmaceuticalsReceptors, SomatostatinTheranostic NanomedicineRadiopharmaceuticalsReceptors, Somatostatinneuroendocrine tumorpeptide receptor radionuclide therapyPRRTsomatostatin receptortheranostics

Identifiers

PMID30613284
PMCPMC6299695
OpenAlexW2902846077

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.