Evidence map›Paper›PMID 30613166›Full record

ArticleHepatic medicine : evidence and research2019

Practical steps to improve chronic hepatitis C treatment in people with opioid use disorder.

Carlos Roncero, Pablo Ryan, Richard Littlewood, Juan Macías, Juan Ruiz, Pedro Seijo, Raúl Felipe Palma-Álvarez, Pablo Vega

Open access · goldAbstract read
In one paragraph

Article in Hepatic medicine : evidence and research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. [Hepatitis C elimination among drug users in China: challenges, strategies and experiences].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Carlos RonceroPsychiatric Service, University of Salamanca Health Care Complex, Institute of Biomedicine of Salamanca, University of Salamanca, Salamanca, Spain, croncero@saludcastillayleon.es.
Pablo RyanInternal Medicine Service, University Hospital Infanta Leonor, Madrid, Spain.
Richard Littlewoodapplied strategic, London, UK.
Juan MacíasDepartment of Infectious Diseases and Microbiology, Valme University Hospital, Seville, Spain.
Juan RuizProvincial Center of Drug Addiction, Malaga, Spain.
Pedro SeijoAddiction Treatment Center of Villamartín, Cádiz, Spain.
Raúl Felipe Palma-ÁlvarezAddiction and Dual Diagnosis Unit, Vall Hebron University Hospital, Barcelona, Spain.
Pablo VegaSpanish Society of Dual Diagnosis, Bilbao, Spain.
Hospital Universitario de Valme · ESInternational Institute for Strategic Studies · GBUniversidad Complutense de Madrid · ESUniversidad de Salamanca · ESUniversitat Autònoma de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPeople with a history of injecting drugs have high prevalence of hepatitis C virus (HCV) infection, and many have opioid use disorder (OUD). Modern HCV therapies with improved efficacy and tolerability are available, but access is often limited for this group, who may be underserved for health care and face social inequity. This work develops practical steps to improve HCV care in this population.

methodsPractical steps to improve HCV care in OUD populations were developed based on clinical experience from Spain, structured assessment of published evidence.

resultsOptions for improving care at engagement/screening stages include patient education programs, strong provider-patient relationship, peer support, and adoption of rapid effective screening tools. To facilitate work up/treatment, start options include simplified work up process, integration of HCV and OUD care, and continuous psychosocial support prior, during, and after HCV treatment.

conclusionIt is important to plan on local basis to set up a joint integrated approach between specific drug treatment services and local points of HCV care. The elements for a specific integrated program should be chosen from options identified, including education services, peer input, organization to make HCV screening and treatment easier by co-location of services, and wider access to prescribing direct-acting antiviral (DAA) therapy.

Indexed as

eliminationHCVopioid use disorderpractical recommendationstreatment

Identifiers

PMID30613166
PMCPMC6307489
OpenAlexW2906236772

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.