Evidence map›Paper›PMID 30612812›Full record

Observational studyThe Journal of pediatrics2019

Black Race Is Associated with a Lower Risk of Bronchopulmonary Dysplasia.

Rita M Ryan, Rui Feng, Catalina Bazacliu, Thomas W Ferkol, Clement L Ren, Thomas J Mariani, Brenda B Poindexter, Fan Wang, Paul E Moore, Prematurity and Respiratory Outcome Program (PROP) Investigators

Open access · greenAbstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in The Journal of pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 49 citations in OpenAlex.

  1. Trial
  2. Human milk feeding and wheeze in Black infants born preterm.Journal of perinatology : official journal of the California Perinatal Association · 2022
    Trial
  3. Review
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Review
  9. Article
  10. Article
  11. Early Origins of Chronic Obstructive Pulmonary Disease: Prenatal and Early Life Risk Factors.International journal of environmental research and public health · 2023
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Tracheal aspirate transcriptomic and miRNA signatures of extreme premature birth with bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2021
    Article
  19. Racial and ethnic disparities in outcomes through 1 year of life in infants born prematurely: a population based study in California.Journal of perinatology : official journal of the California Perinatal Association · 2021
    Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 16 institutions in 1 country.

Rita M RyanDepartment of Pediatrics, Medical University of South Carolina, Charleston, SC. Electronic address: ryanr@musc.edu.
Rui FengDepartment of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, PA.
Catalina BazacliuDepartment of Pediatrics, University of Florida, Gainesville, FL.
Thomas W FerkolDepartment of Pediatrics, Washington University, St. Louis, MO.
Clement L RenDivision of Pediatric Pulmonology, Allergy and Sleep Medicine, Department of Pediatrics, Indiana University, Indianapolis, IN.
Thomas J MarianiDepartment of Pediatrics, University of Rochester, Rochester, NY.
Brenda B PoindexterPerinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Fan WangDepartment of Molecular Cardiology, Lerner Research Institute, The Cleveland Clinic, Cleveland, OH.
Paul E MooreDepartment of Pediatrics, Vanderbilt University, Nashville, TN.
Prematurity and Respiratory Outcome Program (PROP) Investigators
University of California, San Francisco · USCincinnati Children's Hospital Medical Center · USUniversity of Pennsylvania · USUniversity of Rochester · USVanderbilt University · USDuke University · USDrexel University · USMedical University of South Carolina · USAlbert Einstein College of Medicine · USChildren's National · USCleveland Clinic Lerner College of Medicine · USIndiana University · USIndiana University – Purdue University Indianapolis · USUniversity of Denver · USUniversity of Florida · USWashington University in St. Louis · US

Funding

VISUAL INDICES OF NEUROTOXICITYP30ES001247 · NIEHS · UNIVERSITY OF ROCHESTER · PI Sally W Thurston · 1985 to 2026
$42.8M
Data Coordinating Center for the Prematurity and Respiratory Outcomes ProgramU01HL101794 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI SCHMIDT, BARBARA · 2010 to 2014
$10.3M
Gastrin-Releasing Peptide and Bronchopulmonary DysplasiaR01HL105702 · NHLBI · DUKE UNIVERSITY · PI COTTEN, CHARLES MICHAEL, DAVIS, STEPHANIE DUGGINS · 2011 to 2015
$2.8M
Biomarkers of Immunologic Function and Preterm Respiratory OutcomesU01HL101800 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI CHOUGNET, CLAIRE A., JOBE, ALAN H · 2010 to 2014
$2.5M
Functional and Lymphocytic Markers of Respiratory Morbidity in Hyperoxic PreemiesU01HL101813 · NHLBI · UNIVERSITY OF ROCHESTER · PI MARIANI, THOMAS J, PRYHUBER, GLORIA S · 2010 to 2014
$2.4M
Improving Prematurity-related Respiratory Outcomes at Vanderbilt (IMPROV)U01HL101456 · NHLBI · VANDERBILT UNIVERSITY · PI ASCHNER, JUDY LYNN · 2010 to 2014
$2.4M
UCSF Clinical Research Center for Prematurity and Respiratory Outcomes ProgramU01HL101798 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BALLARD, PHILIP L., KELLER, ROBERTA L · 2010 to 2014
$2.1M
Influence of the Enteric Microbiome on the Genesis of Bronchopulmonary DysplasiaU01HL101465 · NHLBI · WASHINGTON UNIVERSITY · PI FERKOL, THOMAS W, WARNER, BARBARA B · 2010 to 2014
$2.1M
NHLBI NIH HHS R01 HL105702NHLBI NIH HHS U01 HL101456NHLBI NIH HHS U01 HL101465NHLBI NIH HHS U01 HL101794NHLBI NIH HHS U01 HL101798NHLBI NIH HHS U01 HL101800NHLBI NIH HHS U01 HL101813NIEHS NIH HHS P30 ES001247
6 · The paper itself

Abstract

objectiveTo use a large current prospective cohort of infants <29 weeks to compare bronchopulmonary dysplasia (BPD) rates in black and white infants. STUDY

designThe Prematurity and Respiratory Outcome Program (PROP) enrolled 835 infants born in 2011-2013 at <29 weeks of gestation; 728 black or white infants survived to 36 weeks postmenstrual age (PMA). Logistic regression was used to compare BPD outcomes (defined as supplemental oxygen requirement at 36 weeks PMA) between the races, adjusted for gestational age (GA), antenatal steroid use, intubation at birth, and surfactant use at birth.

resultsOf 707 black or white infants with available BPD outcomes, BPD was lower in black infants (38% vs 45%), even though they were of significantly lower GA. At every GA, BPD was more common in white infants. The aOR for BPD was 0.60 (95% CI, 0.42-0.85; P = .004) for black infants compared with white infants after adjusting for GA. Despite the lower rate of BPD, black infants had a higher rate of first-year post-prematurity respiratory disease (black, 79%; white, 63%).

conclusionsIn this large cohort of recently born preterm infants at <29 weeks GA, compared with white infants, black infants had a lower risk of BPD but an increased risk of persistent respiratory morbidity.

Indexed as

Black or African AmericanInfant, PrematureBronchopulmonary DysplasiaFollow-Up StudiesGestational AgeHospitalizationHumansInfant, Premature, DiseasesIntensive Care Units, NeonatalMorbidityProspective StudiesRisk AssessmentRisk FactorsSurvival RateUnited StatesWhite People

Identifiers

PMID30612812
PMCPMC6458591
OpenAlexW2907636064

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.