Evidence map›Paper›PMID 30612810›Full record

ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2019

Measuring Discomfort in Health Research Relative to Everyday Events and Routine Care: An Application to Sexual and Gender Minority Youth.

Kathryn Macapagal, Emily Bettin, Margaret Matson, Ashley Kraus, Celia B Fisher, Brian Mustanski

Open access · greenAbstract read
In one paragraph

Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Reactions to Sexual, Substance Use, and Mental Health Surveys Among Rural Sexual Minority Men.Health education & behavior : the official publication of the Society for Public Health Education · 2025
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kathryn MacapagalDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Institute for Sexual and Gender Minority Health and Wellbeing, Northwestern University, Chicago, Illinois. Electronic address: kathryn.macapagal@northwestern.edu.
Emily BettinDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Institute for Sexual and Gender Minority Health and Wellbeing, Northwestern University, Chicago, Illinois.
Margaret MatsonDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Institute for Sexual and Gender Minority Health and Wellbeing, Northwestern University, Chicago, Illinois.
Ashley KrausDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Institute for Sexual and Gender Minority Health and Wellbeing, Northwestern University, Chicago, Illinois.
Celia B FisherCenter for Ethics Education and Department of Psychology, Fordham University, Bronx, New York.
Brian MustanskiDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Institute for Sexual and Gender Minority Health and Wellbeing, Northwestern University, Chicago, Illinois.
Northwestern University · USFordham University · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Northwestern University Clinical and Translational Science Institute (NUCATS)TL1TR001423 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MCCOLLEY, SUSANNA A · 2015 to 2023
$5.0M
Ethics in HIV Prevention Research Involving LGBT YouthR01MD009561 · NIMHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI FISHER, CELIA B, MUSTANSKI, BRIAN · 2014 to 2017
$2.0M
NCATS NIH HHS TL1 TR001423NCATS NIH HHS UL1 TR001422NIMHD NIH HHS R01 MD009561
6 · The paper itself

Abstract

purposeUnderstanding how sexual and gender minority (SGM) youth's comfort with research procedures compares to their comfort with everyday experiences and routine health care can help calibrate decisions about whether a study meets minimal risk criteria. We sought to quantify SGM adolescents' comfort with sexual health research relative to everyday events and activities often cited as benchmarks of minimal risk.

methodsA total of 616 SGM adolescents in the United States (mean age = 15.7 years, 41.7% racial/ethnic minority) completed online survey questions assessing sexual behavior, SGM identity, and a 53-item Measure of Adolescent Comfort with Clinical, Research, and Everyday Events that assessed comfort on a 7-point scale (1 = extremely uncomfortable and 7 = extremely comfortable).

resultsThe Everyday Events for Adolescents domain had the lowest mean comfort score (M = 3.49, standard deviation [SD] = .58) and was significantly lower than the Routine Medical and Psychological Tests domain (M = 4.43, SD = .92) and the HIV/Sexual Health Research Procedures domain (M = 4.19, SD = .94). Eleven of 17 items on the HIV/Sexual Health Research Procedures domain were ranked as more comfortable than a neutral rating of "neither comfortable nor uncomfortable." Higher levels of parental acceptance predicted greater levels of comfort across all four domains of the Measure of Adolescent Comfort with Clinical, Research, and Everyday Events. Participants who were out to their parents expressed greater comfort with both SGM Identity and Sexual Health-related procedures and events as well as HIV/Sexual Health Research Procedures.

conclusionsOverall participants expressed equal or more comfort with research procedures than with everyday life experiences. These findings indicate that common sexual health research procedures may meet minimal risk criteria among SGM adolescent populations.

Indexed as

Health Services ResearchPrimary Health CareResearch DesignSexual HealthAdolescentEthnicityFemaleHumansInternetMaleSexual and Gender MinoritiesSexual BehaviorSurveys and QuestionnairesAdolescent sexual behaviorAdolescent sexual healthHIV/AIDSResearch ethics

Identifiers

PMID30612810
PMCPMC6478526
OpenAlexW2907552553

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.