Evidence map›Paper›PMID 30612547›Full record

ArticleBMC cardiovascular disorders2019

The influence of LV geometry on the occurrence of abnormal exercise tests in athletes.

Danny A J P van de Sande, Jan Hoogsteen, Pieter A Doevendans, Hareld M C Kemps

Open access · goldAbstract readComparative Study
In one paragraph

Article in BMC cardiovascular disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Danny A J P van de SandeDepartment of Cardiology, Máxima Medical Center, De Run 4600, 5504, DB, Veldhoven, The Netherlands. d.vandesande@mmc.nl.ORCID 0000-0002-8553-5025
Jan HoogsteenDepartment of Cardiology, Máxima Medical Center, De Run 4600, 5504, DB, Veldhoven, The Netherlands.
Pieter A DoevendansDepartment of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Hareld M C KempsDepartment of Cardiology, Máxima Medical Center, De Run 4600, 5504, DB, Veldhoven, The Netherlands.
Radboud University Nijmegen · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies revealed a high rate of abnormal exercise test (ET) results in the absence of obstructive coronary artery disease (CAD) in asymptomatic athletes. The physiological background of this phenomenon is not well established. In particular, it is unclear whether sports-induced morphological cardiac adaptations are determinants of abnormal ET results. The main objective of this study was to investigate if healthy asymptomatic recreational and competitive athletes with abnormal ET results without obstructive CAD have a higher LV mass when compared with athletes with normal ET results.

methodsSeventy-three athletes with abnormal ET results without presence of obstructive CAD underwent echocardiographic assessment of LV mass, systolic and diastolic measurements. These data were compared with data from 73 athletes with normal ET results, matched for gender, age, body composition, sports characteristics and exercise capacity.

resultsNo significant increase in LV mass (161.9 ± 39 g vs. 166.9 ± 42.1 g, p = 0.461) was found between groups. Athletes with abnormal ET results had a significant thicker IVSd (9.7 ± 1.8 mm vs. 9.0 ± 1.7 mm, p = 0.014), higher IVSd/PWTd ratio (1.08 ± 0.20 vs. 1.00 ± 0.12, p = 0.011) and deceleration time (DT) was prolonged ((225.14 ± 55.08 vs. 199.96 ± 34.65, p = 0.003).

conclusionAthletes with abnormal ET result did not show a higher in LV mass when compared to athletes with a normal ET result. However, a pattern of asymmetric cardiac remodeling, together with altered diastolic function is present. Due to small differences, cardiac remodeling only plays a limited role in the occurrence of positive ET results in athletes.

Indexed as

AthletesCardiomegaly, Exercise-InducedEchocardiography, Doppler, ColorExercise TestVentricular Function, LeftVentricular RemodelingAdaptation, PhysiologicalAdultFemaleHeart VentriclesHumansMaleMiddle AgedPredictive Value of TestsProspective StudiesReproducibility of ResultsAthletesCardiac remodelingDiagnostic accuracyEchocardiographyExercise testing

Identifiers

PMID30612547
PMCPMC6322237
OpenAlexW2929617966

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.