ArticleJournal of the American Heart Association2019
Association Between Wait Time for Transcatheter Aortic Valve Replacement and Early Postprocedural Outcomes.
Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Transcatheter Aortic Valve Replacement vs. Surgical Aortic Valve Replacement for Long-Term Mortality Due to Stroke and Myocardial Infarction: A Meta-Analysis during the COVID-19 Pandemic.Medicina (Kaunas, Lithuania) · 2022Pooled it
- Efficacy and Safety of Emergent Transcatheter Aortic Valve Implantation in Patients with Acute Decompensated Aortic Stenosis: Systematic Review and Meta-Analysis.Journal of interventional cardiology · 2021Pooled it
- Triage Considerations for Patients Referred for Structural Heart Disease Intervention During the COVID-19 Pandemic: An ACC/SCAI Position Statement.JACC. Cardiovascular interventions · 2020Guideline
- Optimizing patient triage on the waiting list for transcatheter aortic valve replacement: the clinical utility of the cardiac damage staging system.European heart journal. Quality of care & clinical outcomes · 2026Article
- The Clinical and Economic Consequences of Delayed Transcatheter Aortic Valve Replacement.Structural heart : the journal of the Heart Team · 2026Article
- Impacts of Hospital Data Breach on Healthcare Quality.Health services research · 2025Article
- Acute Valve Syndrome in Aortic Stenosis.Structural heart : the journal of the Heart Team · 2025Article
- Predictors of requirement for urgent versus elective TAVI and comparison of short and medium outcomes.The British journal of cardiology · 2025Article
- Prognostic impact of muscle ultrasound-guided diagnosis of sarcopenia in older adults with severe aortic stenosis.European geriatric medicine · 2024Article
- Sarcopenia and aortic valve disease.Heart (British Cardiac Society) · 2024Review
- Impact of Neighborhood Social Deprivation on Delays to Access for Transcatheter Aortic Valve Replacement: Wait-Times and Clinical Consequences.Journal of the American Heart Association · 2024Article
- Transcatheter Aortic Valve Implantation Wait-Time Management: Derivation and Validation of the Canadian TAVI Triage Tool (CAN3T).Journal of the American Heart Association · 2024Article
- Cardiovascular outcomes of emergent vs elective transcatheter aortic valve replacement in severe aortic stenosis: regression matched meta-analysis.American journal of cardiovascular disease · 2024Review
- Regional Differences in Outcomes for Patients Undergoing Transcatheter Aortic Valve Replacement in New York State and Ontario.The Canadian journal of cardiology · 2023Observational
- Financial Incentives for Transcatheter Aortic Valve Implantation in Ontario, Canada: A Cost-Utility Analysis.Journal of the American Heart Association · 2022Article
- Impact of wait times on late postprocedural mortality after successful transcatheter aortic valve replacement.Scientific reports · 2022Article
- Association of Use of Electronic Appointment Reminders With Waiting Times in the Veterans Affairs Health System.JAMA network open · 2022Article
- Urgent transcatheter aortic valve implantation in an all-comer population: a single-centre experience.BMC cardiovascular disorders · 2021Article
- Lessons for Treating Structural Heart Patients during the COVID-19 Pandemic and Beyond.Structural heart : the journal of the Heart Team · 2021Article
- Indirect Impact of the COVID-19 Pandemic on Activity and Outcomes of Transcatheter and Surgical Treatment of Aortic Stenosis in England.Circulation. Cardiovascular interventions · 2021Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Rapid growth in transcatheter aortic valve replacement ( TAVR ) demand has translated to inadequate access, reflected by prolonged wait times. Increasing wait times are associated with important adverse outcomes while on the wait-list; however, it is unknown if prolonged wait times influence postprocedural outcomes. Our objective was to determine the association between TAVR wait times and postprocedural outcomes. Methods and Results In this population-based study in Ontario, Canada, we identified all TAVR procedures between April 1, 2010, and March 31, 2016. Wait time was defined as the number of days between initial referral and the procedure. Primary outcomes of interest were 30-day all-cause mortality and all-cause readmission. Multivariable regression models incorporated wait time as a nonlinear variable, using cubic splines. The study cohort included 2170 TAVR procedures, of which 1741 cases were elective and 429 were urgent. There was a significant, nonlinear relationship between TAVR wait time and post- TAVR 30-day mortality, as well as 30-day readmission. We observed an increased hazard associated with shorter wait times that diminished as wait times increased. This statistically significant nonlinear relationship was seen in the unadjusted model as well as after adjusting for clinical variables. However, after adjusting for case urgency status, there was no relationship between wait times and postprocedural outcomes. In sensitivity analyses restricted to either only elective or only urgent cases, there was no relationship between wait times and postprocedural outcomes. Conclusions Wait time has a complex relationship with postprocedural outcomes that is mediated entirely by urgency status. This suggests that further research should elucidate factors that predict hospitalization requiring urgent TAVR while on the wait list.
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