Evidence map›Paper›PMID 30612355›Full record

ArticleEnvironmental science and pollution research international2019

The potential modulatory role of herbal additives against Cd toxicity in human, animal, and poultry: a review.

Asmaa F Khafaga, Mohamed E Abd El-Hack, Ayman E Taha, Shaaban S Elnesr, Mahmoud Alagawany

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 88 citations in OpenAlex.

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  4. Impact of dietary zinc nanoparticles and probiotics on broiler health and productivity.Journal of advanced veterinary and animal research · 2025
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  10. Frontiers in molecular biosciences · 2024
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  19. Approaches to prevent and control Campylobacter spp. colonization in broiler chickens: a review.Environmental science and pollution research international · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Asmaa F KhafagaDepartment of Pathology, Faculty of Veterinary Medicine, Alexandria University, Edfina, 22758, Egypt.
Mohamed E Abd El-HackDepartment of Poultry, Faculty of Agriculture, Zagazig University, Zagazig, 44511, Egypt. m.ezzat@zu.edu.eg.
Ayman E TahaDepartment of Animal Husbandry and Animal Wealth Development, Faculty of Veterinary Medicine, Alexandria University, Edfina, 22578, Egypt.
Shaaban S ElnesrDepartment of Poultry Production, Faculty of Agriculture, Fayoum University, Fayoum, 63514, Egypt.
Mahmoud AlagawanyDepartment of Poultry, Faculty of Agriculture, Zagazig University, Zagazig, 44511, Egypt. dr.mahmoud.alagwany@gmail.com.
Alexandria University · EGZagazig University · EGFayoum University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cadmium (Cd) is a heavy and toxic metal and easily absorbed by animals and plants; subsequently, it is an environmental risk factor with several toxic effects in humans and animals. The main pathway of human or animal exposure to Cd is through its ingestion by water or food and by particles or fume inhalation during industrial processes. With continuous exposure to small levels of cadmium, it is being deposited in different tissues day after day, causing toxic effects on the liver, kidney, and testes. Long-term exposure to this toxic metal resulted in inflammatory infiltration, necrosis of hepatocytes, degenerative changes in testis tissues, reduction in spermatocytes, degeneration in renal tubules, and hypertrophy of renal epithelium. Therefore, we need an effective treatment to overcome cadmium poisoning. Thus, in the current review, we try to provide compiled reports and summarize information about the toxicological effects of Cd in human, animals, and poultry. This review also provides updated information about the protective actions of herbs and herbal extracts and their role as an effective strategy in reducing or preventing serious health problems and tissue damage in response to Cd toxicity.

Indexed as

Plants, MedicinalAnimalsCadmiumCadmium PoisoningCinnamomum zeylanicumHumansInactivation, MetabolicKidneyMaleNigella sativaPanaxPlant ExtractsPoultryTeaTestisCadmiumPlant ExtractsTeaAnimalsCadmium toxicityHeavy metalsHerbsPoultryTherapeutic action

Identifiers

PMID30612355
OpenAlexW2907726168

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.