Evidence map›Paper›PMID 30612348›Full record

ArticleEnvironmental science and pollution research international2020

Acute oral toxicity study on Wistar rats fed microalgal protein hydrolysates from Bellerochea malleus.

Ines Barkia, Hanen Ketata Bouaziz, Tahiya Sellami Boudawara, Lotfi Aleya, Ali Faouzi Gargouri, Nazamid Saari

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  7. Advances in nanotechnology, nanopollution, nanotoxicology, and nanomedicine.Environmental science and pollution research international · 2020
    Article
  8. Drug target insights
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Ines BarkiaDepartment of Food Science, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
Hanen Ketata BouazizAnimal Physiology Laboratory, Faculty of Sciences, University of Sfax,, 3000, Sfax, Tunisia.
Tahiya Sellami BoudawaraHistopathology Laboratory, University of Sfax, CHU Habib Bourguiba, 3029, Sfax, Tunisia.
Lotfi AleyaLaboratoire Chrono-Environnement, UMR 6249 CNRS, Besançon, France. lotfi.aleya@univ-fcomte.fr.
Ali Faouzi GargouriLaboratory of Molecular Biotechnology of Eucaryotes, Centre of Biotechnology of Sfax (CBS), CHU Habib Bourguiba,, 3029, Sfax, Tunisia.
Nazamid SaariDepartment of Food Science, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
Universiti Putra Malaysia · MYUniversity of Sfax · TNCentre National de la Recherche Scientifique · FRCentre of Biotechnology of Sfax · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein hydrolysates and bioactive peptides from various protein sources have demonstrated their effectiveness for the prevention of illness and the improvement of symptoms from several diseases. In particular, the use of microalgae to generate bioactive peptides has received a growing interest because of their potential to be cultivated on non-arable land and high nutritional value. However, scant research is available on the toxicity of peptide-based preparations. The present study aims to evaluate the toxicity of microalgal protein hydrolysates (MPH) from one marine species of microalgae (Bellerochea malleus) to determine the feasibility of their use for functional food applications. Results showed that the oral administration of MPH at three doses (D1, 100 mg kg

Indexed as

MicroalgaeAdministration, OralAnimalsMaleMalleusOrgan SizeProtein HydrolysatesRatsRats, WistarToxicity Tests, AcuteProtein HydrolysatesKidneyLiverMicroalgal protein hydrolysatesRatsToxicity

Identifiers

PMID30612348
OpenAlexW2907060741

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.