Evidence map›Paper›PMID 30612317›Full record

ArticleApoptosis : an international journal on programmed cell death2019

Cancer therapeutics based on BCL-2 functional conversion.

Martin C Pearce, Arnold C Satterthwait, Xiao-Kun Zhang, Siva Kumar Kolluri

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Apoptosis : an international journal on programmed cell death, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Martin C PearceCancer Research Laboratory, Department of Environmental & Molecular Toxicology, Oregon State University, Corvallis, OR, 97331, USA.
Arnold C SatterthwaitSanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA, 92037, USA.
Xiao-Kun ZhangSanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA, 92037, USA.
Siva Kumar KolluriCancer Research Laboratory, Department of Environmental & Molecular Toxicology, Oregon State University, Corvallis, OR, 97331, USA. siva.kolluri@oregonstate.edu.

Funding

Bcl-2 as a target in cancerR21CA249627 · NCI · OREGON STATE UNIVERSITY · PI KOLLURI, SIVA KUMAR · 2021 to 2022
$378k
NCI NIH HHS R21 CA249627
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ApoptosisAnimalsApoptosis Regulatory ProteinsCell SurvivalHumansInhibitor of Apoptosis ProteinsMolecular Targeted TherapyNeoplasmsNuclear Receptor Subfamily 4, Group A, Member 1OligopeptidesProto-Oncogene Proteins c-bcl-2Tumor BurdenApoptosis Regulatory ProteinsBCL2 protein, humanInhibitor of Apoptosis ProteinsNR4A1 protein, humanNuclear Receptor Subfamily 4, Group A, Member 1Oligopeptidesphenylalanyl-seryl-arginyl-seryl-leucyl-histidyl-seryl-leucyl-leucineProto-Oncogene Proteins c-bcl-2

Identifiers

PMID30612317
PMCPMC12190864

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.