Evidence map›Paper›PMID 30612315›Full record

ArticleJournal of cancer education : the official journal of the American Association for Cancer Education2020

Racial/Ethnic Differences in Comprehension of Biospecimen Collection: a Nationwide University of Rochester Cancer Center NCI Community Oncology Research Program Study.

Matthew Asare, Charles E Heckler, Eva Culakova, Charles S Kamen, Amber S Kleckner, Lori M Minasian, David S Wendler, Michelle Feige, Carol J Weil, Joan Long and 5 more

Abstract read
In one paragraph

Article in Journal of cancer education : the official journal of the American Association for Cancer Education, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Matthew AsareDepartment of Public Health, Robbins College of Health and Human Sciences, Baylor University, One Bear Place, Waco, TX, 97343, USA. matt_asare@baylor.edu.
Charles E HecklerJames P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.
Eva CulakovaJames P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.
Charles S KamenJames P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.
Amber S KlecknerJames P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.
Lori M MinasianNational Cancer Institute (NCI), Bethesda, MD, USA.
David S WendlerNational Institute of Health (NIH), Bethesda, MD, USA.
Michelle FeigeAssociation for the Accreditation of Human Research Protection Programs, Inc. (AAHRPP), Washington, DC, USA.
Carol J WeilNational Cancer Institute (NCI), Bethesda, MD, USA.
Joan LongCancer Research Consortium of West Michigan NCORP, Grand Rapids, MI, USA.
Sharon K ColeDayton Clinical Oncology Program, Dayton, OH, USA.
Adedayo A OnitiloWisconsin NCORP, Marshfield, WI, USA.
Luke J PepponeJames P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.
Gary R MorrowJames P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.
Michelle C JanelsinsJames P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.

Funding

URCC NCORP Research BaseUG1CA189961 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, KAREN M. MUSTIAN · 2014 to 2026
$67.7M
UNIVERSITY OF ROCHESTER--CCOP RESEARCH BASEU10CA037420 · NCI · UNIVERSITY OF ROCHESTER · PI MORROW, GARY R · 1985 to 2014
$21.1M
Cancer Control Research Training Curriculum (R25T)R25CA102618 · NCI · UNIVERSITY OF ROCHESTER · PI JANELSINS, MICHELLE C, MORROW, GARY R · 2004 to 2018
$6.7M
Clinical and Translational Cancer Control Research Training ProgramT32CA102618 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, Gary R Morrow · 2019 to 2026
$2.7M
Interventions Targeting Inflammation for Chemotherapy-Related Cognitive ProblemsK07CA168886 · NCI · UNIVERSITY OF ROCHESTER · PI JANELSINS, MICHELLE C · 2013 to 2017
$724k
Research and clinical care without informed consentZIACL010537 · CLC · CLINICAL CENTER · PI WENDLER, DAVID S · 2014 to 2025
$0k
NCI NIH HHS K07 CA168886NCI NIH HHS R25 CA102618NCI NIH HHS T32 CA102618NCI NIH HHS U10 CA037420NCI NIH HHS UG1 CA189961
6 · The paper itself

Abstract

To examine whether (a) non-minority participants differed from racial minority participants in the understanding of biospecimens collected for research purposes, (b) patients differed from comparison group in their understanding of the ways their biospecimens could be used by researchers, and (c) participants received adequate information before consenting to donate blood for research studies. We analyzed cross-sectional data from female breast cancer patients scheduled to receive chemotherapy at the National Cancer Institute (NCI) Community Oncology Research Program (NCORP) clinical sites and a healthy comparison group. After reading a consent form related to biospecimens and consenting to participate in a clinical trial, participants' understanding of biospecimen collection was evaluated. Linear models were used to compare scores between non-minority and racial minority participants as well as cancer and non-cancer comparisons adjusting for possible confounding factors. A total of 650 participants provided evaluable data; 592 were non-minority (Caucasian) and 58 participants were a racial minority (71% Black and 29% other). There were 427 cancer patients and 223 comparisons. Non-minority participants scored higher than racial minorities on relevance-to-care items (diff. = 0.48, CI 0.13-0.80, p = 0.001). Comparison group scored higher than cancer patients on relevance-to-care items (diff. = 0.58, CI 0.37-0.78). A moderate number of the participants exhibited a poor understanding of biospecimen collection across all racial/ethnic backgrounds, but racial minority participants' scores remained lower in the relevance-to-care subscale even after adjusting for education and reading level. Differences were also noted among the patients and comparison group. Researchers should facilitate comprehension of biospecimen collection for all study participants, especially racial minority participants.

Indexed as

ComprehensionHealth Status DisparitiesAdultAgedAged, 80 and overBiological Specimen BanksBlack or African AmericanBreast NeoplasmsCase-Control StudiesClinical Trials as TopicCross-Sectional StudiesEthnicityFemaleHealth Knowledge, Attitudes, PracticeHumansMiddle AgedBiospecimensConsentConsent formDisparitiesRace

Identifiers

PMID30612315
PMCPMC6612536

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.