ArticleAnnals of intensive care2019
Long-term health-related quality of life of critically ill patients with haematological malignancies: a prospective observational multicenter study.
Article in Annals of intensive care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Factors influencing long-term health-related quality of life among intensive care unit survivors: a mixed-methods systematic review.Frontiers in public health · 2026Pooled it
- Acute respiratory distress syndrome in patients with cancer: the YELENNA prospective multinational observational cohort study.Intensive care medicine · 2025Observational
- Post-Traumatic Stress and Stressor-Related Disorders in Hematological Malignancies: A Review.Journal of clinical medicine · 2025Review
- Latent profile analysis of fear of progression in Chinese hematologic malignancy survivors.Scientific reports · 2025Article
- Long-term survival and functional outcomes of critically ill patients with hematologic malignancies: a Canadian multicenter prospective study.Intensive care medicine · 2024Observational
- Long-term, patient-centered, frailty-based outcomes of older critical illness survivors from the emergency department: a post hoc analysis of the LIFE Study.BMC geriatrics · 2024Observational
- Prediction of post-traumatic stress disorder in family members of ICU patients: a machine learning approach.Intensive care medicine · 2024Article
- High-value care for critically ill oncohematological patients: what do we know thus far?Critical care science · 2023Review
- Article
- One-year Mortality of Cancer Patients with an Unplanned ICU Admission: A Cohort Analysis Between 2008 and 2017 in the Netherlands.Journal of intensive care medicine · 2022Article
- Health-related quality of life in critically ill survivors: specific impact of cardiac arrest in non-shockable rhythm.Annals of intensive care · 2021Article
- Outcome of cancer patients considered for intensive care unit admission in two university hospitals in the Netherlands: the danger of delayed ICU admissions and off-hour triage decisions.Annals of intensive care · 2021Article
- Long-term quality of life in necrotizing soft-tissue infection survivors: a monocentric prospective cohort study.Annals of intensive care · 2021Article
- One-year survival of patients with high-grade glioma discharged alive from the intensive care unit.Journal of neurology · 2021Observational
- [Functional evolution and mood of patients after admission for COVID-19 to intensive care unit].RehabilitacionArticle
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Authors and funding
22 authors at 14 institutions in 2 countries.
Funding
Abstract
backgroundAlthough outcomes of critically ill patients with haematological malignancies (HMs) have been fully investigated in terms of organ failure and mortality, data are scarce on health-related quality of life (HRQOL) in this population. We aim to assess post-intensive care unit (ICU) burden and HRQOL of critically ill patients with HMs and to identify risk factors for quality-of-life (QOL) impairment.
resultsIn total, 1011 patients with HMs who required ICU admission in 17 ICUs in France and Belgium were included in the study; 278 and 117 patients were evaluated for QOL at 3 months and 1 year, respectively, after ICU discharge. HRQOL was determined by applying the interview form of the Short Form 36 (SF-36) questionnaire. Psychological distress symptoms were evaluated using the Hospital Anxiety Depression Score (HADS) and the Impact of Event Scale (IES). In-hospital mortality rates at 3 months and 1 year were, respectively, 39.1, 50.7 and 57.2%, respectively. At 3 months, median [IQR] physical and mental component summary scores (PCS and MCS) (SF-36) were 37 [28-46] and 51 [45-58], respectively. PCS was lower in ICU patients with HMs when compared to general ICU septic patients (52 [5-13], p = 0.00001). The median combined HAD score was 8 [5-13], and the median IES score was 8 [3-16]. However, recovery during the first year after ICU discharge was not consistent in all dimensions of HRQOL. Three months after ICU discharge, the maximum daily Sequential Organ Failure Assessment score and status of the underlying malignancy at ICU admission were significantly associated with MCS impairment (- 0.54 points [95% CI - 0.99; - 0.1], p = 0.018 and - 4.83 points [95% CI - 8.44; - 1.22], p = 0.009, respectively).
conclusionHRQOL is strongly impaired in critically ill patients with HMs at 3 months and 1 year after ICU discharge. Organ failure and disease status are strongly associated with QOL. The kinetic evaluation of QOL at 3 months and 1 year offers the opportunity to focus on QOL aspects that may be improved by therapeutic interventions during the first year after ICU discharge.
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