Evidence map›Paper›PMID 30612203›Full record

ArticlePediatric nephrology (Berlin, Germany)2019

Haemodiafiltration use in children: data from the Italian Pediatric Dialysis Registry.

Fabio Paglialonga, Enrico Vidal, Carmine Pecoraro, Isabella Guzzo, Mario Giordano, Bruno Gianoglio, Ciro Corrado, Rosa Roperto, Ilse Ratsch, Salvatore Luzio and 6 more

Abstract read
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In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 1 country.

Fabio PaglialongaPediatric Nephrology, Dialysis and Transplant Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122, Milan, Italy. fabio.paglialonga@policlinico.mi.it.ORCID 0000-0002-9912-3371
Enrico VidalPediatric Nephrology, Dialysis and Transplant Unit, Department of Women's and Children's Health, University-Hospital, Padua, Italy.
Carmine PecoraroNephrology and Dialysis Unit, Santobono Children's Hospital, Naples, Italy.
Isabella GuzzoNephrology and Dialysis Unit, Department of Pediatrics, "Bambino Gesù" Children's Hospital-IRCCS, Rome, Italy.
Mario GiordanoNephrology Division and Dialysis Unit, Giovanni XXIII Children's Hospital, Bari, Italy.
Bruno GianoglioNephrology Dialysis and Transplantation Unit, Regina Margherita University Hospital, Turin, Italy.
Ciro CorradoPediatric Nephrology and Dialysis Unit, Children's Hospital G. Di Cristina, Palermo, Italy.
Rosa RopertoNephrology and Dialysis Unit, Meyer Children's Hospital, Florence, Italy.
Ilse RatschUniversity Department of Pediatrics, United Hospitals of Ancona, Ancona, Italy.
Salvatore LuzioDialysis Unit, Paediatric Nephrology and Dialysis Department, G Gaslini Children Hospital, Genoa, Italy.
Luisa MurerPediatric Nephrology, Dialysis and Transplant Unit, Department of Women's and Children's Health, University-Hospital, Padua, Italy.
Silvia ConsoloPediatric Nephrology, Dialysis and Transplant Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122, Milan, Italy.
Giovanni PieriPediatric Nephrology, Dialysis and Transplant Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122, Milan, Italy.
Giovanni MontiniPediatric Nephrology, Dialysis and Transplant Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122, Milan, Italy.
Alberto EdefontiPediatric Nephrology, Dialysis and Transplant Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122, Milan, Italy.
Enrico VerrinaDialysis Unit, Paediatric Nephrology and Dialysis Department, G Gaslini Children Hospital, Genoa, Italy.
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITIstituto Giannina Gaslini · ITUniversity of Padua · ITBambino Gesù Children's Hospital · ITMeyer Children's Hospital · ITOspedale Pediatrico Giovanni XXIII · ITOspedale Regina Margherita · ITOspedali Riuniti di Ancona · ITSantobono Children's Hospital · ITUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh volume haemodiafiltration (HDF) is associated with better survival than conventional haemodialysis (HD) in adults, but data concerning its use in children are lacking. The aim of this study was to assess the prevalence of paediatric HDF use and its associated factors in recent years in Italy.

methodsWe retrospectively reviewed the files of patients from the Italian Pediatric Dialysis Registry's database who were registered between January 1, 2004 and December 31, 2016 and treated with extracorporeal dialysis for at least 6 months, looking in particular at modality and its associated factors.

resultsOne hundred forty-one out of 198 patients were treated exclusively with bicarbonate HD (71.2%), 57 with HDF (28.8%). Patients treated with HDF were younger (median 9.7 vs 13.2 years, p = 0.0008), were less often incident patients (52.6% vs 75.9%, p = 0.0031), had longer duration of the HD cycle (26.9 vs 20.8 months, p = 0.0036) and had a longer time to renal transplantation (32 vs 25 months, p = 0.0029) than those treated with bicarbonate HD only. The percentage of patients treated with HDF increased with dialysis vintage (16.9% at 6 months, 38.1% after more than 2 years of dialysis). The use of HDF was stable over time and was more common in the largest centres.

conclusionsOver the observation period, HDF use in Italy has been limited to roughly a quarter of patients on extracorporeal dialysis, in particular to those with high dialysis vintage, younger age or a long expected waiting time to renal transplantation.

Indexed as

AdolescentChildFemaleHemodiafiltrationHumansItalyKidney Failure, ChronicMaleRegistriesRetrospective StudiesChildrenExtracorporeal dialysisHaemodiafiltrationHaemodialysisPaediatric dialysis

Identifiers

PMID30612203
OpenAlexW2908163725

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.