Evidence map›Paper›PMID 30612150›Full record

ArticleChromosoma2019

A new role for Drosophila Aurora-A in maintaining chromosome integrity.

Chiara Merigliano, Elisa Mascolo, Anthony Cesta, Isabella Saggio, Fiammetta Vernì

Abstract read
PubMed Publisher
In one paragraph

Article in Chromosoma, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Chiara MeriglianoDipartimento di Biologia e Biotecnologie "C. Darwin", Sapienza Università di Roma, 00185, Rome, Italy.
Elisa MascoloDipartimento di Biologia e Biotecnologie "C. Darwin", Sapienza Università di Roma, 00185, Rome, Italy.
Anthony CestaDipartimento di Biologia e Biotecnologie "C. Darwin", Sapienza Università di Roma, 00185, Rome, Italy.
Isabella SaggioDipartimento di Biologia e Biotecnologie "C. Darwin", Sapienza Università di Roma, 00185, Rome, Italy. isabella.saggio@uniroma1.it.
Fiammetta VernìDipartimento di Biologia e Biotecnologie "C. Darwin", Sapienza Università di Roma, 00185, Rome, Italy. fiammetta.verni@uniroma1.it.
Sapienza University of Rome · ITNanyang Technological University · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aurora-A is a conserved mitotic kinase overexpressed in many types of cancer. Growing evidence shows that Aurora-A plays a crucial role in DNA damage response (DDR) although this aspect has been less characterized. We isolated a new aur-A mutation, named aur-A

Indexed as

DNA End-Joining RepairEpistasis, GeneticAnimalsAurora Kinase AChromosome AberrationsChromosomes, InsectDNA DamageDNA Ligase ATPDNA Repair EnzymesDrosophila melanogasterDrosophila ProteinsFemaleGenomic InstabilityHistonesMaleMutationaurA protein, DrosophilaAurora Kinase ADNA Ligase ATPDNA Repair EnzymesDrosophila ProteinsHis2Av protein, DrosophilaHistonesProtein Serine-Threonine KinasesTefu protein, DrosophilaAurora-AChromosome aberrationsDrosophilaLigase 4Rad 51

Identifiers

PMID30612150
OpenAlexW2907794841

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.