ArticleGait & posture2019
Weight loss changed gait kinematics in individuals with obesity and knee pain.
Article in Gait & posture, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- A systematic review and meta-analysis of the effect of phonophoresis on patients with knee osteoarthritis.Scientific reports · 2022Pooled it
- Efficacy and safety of radiofrequency treatment for improving knee pain and function in knee osteoarthritis: a meta-analysis of randomized controlled trials.Journal of orthopaedic surgery and research · 2022Pooled it
- Bariatric Surgery in Adults with Obesity: the Impact on Performance, Metabolism, and Health Indices.Obesity surgery · 2021Pooled it
- Combined mode-kinetic chain exercise with and without core stability exercises on patients with knee osteoarthritis.BMC musculoskeletal disorders · 2026Trial
- Trial
- Improved Joint Mobility Associated with Reduced Inflammation Related to Consumption of Nopal Cactus Fruit Juice: Results from a Placebo-Controlled Trial Using Digital Inclinometry to Objectively Document Mobility of All Major Joints.Clinical interventions in aging · 2020Trial
- Radiographic Changes in Patellar Height Following Rapid Weight Loss After Sleeve Gastrectomy: A Retrospective Observational Study.Journal of clinical medicine · 2026Article
- Individualized multimodal integration of optimized dual fluoroscopic imaging registration and finite element modeling for knee joint stress during stair ascent.Medical & biological engineering & computing · 2026Article
- Weight Reduction via Lifestyle Intervention Improves Androgen Levels and Glucose Metabolism in Women of Reproductive Age with Hyperandrogenism: A Real-World Observational Study.Journal of clinical medicine · 2026Article
- Predictive Neuromechanical Simulation Explains Gait Biomechanics in Obesity.bioRxiv : the preprint server for biology · 2026Article
- Gait Biomechanics Across BMI Categories in Adults: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Biomechanical phenotypes of unilateral versus bilateral anterior knee pain: evidence from walking kinematics, kinetics, and symmetry indices.Frontiers in bioengineering and biotechnology · 2026Article
- Prevalence of knee osteoarthritis among elderly persons in India: A systematic review and meta-analysis.Journal of family medicine and primary care · 2025Article
- Global shifts in osteoarthritis subtype trends among older adults due to elevated BMI: an age-period-cohort analysis based on the global burden of disease database.Frontiers in public health · 2025Article
- Does commonly used femoral components of total knee arthroplasty fit well in the Indian population?Journal of clinical orthopaedics and trauma · 2024Article
- Obesity and the risk of multiple or severe frequent knee pain episodes: a 4-year follow-up of the ELSA-Brasil MSK cohort.International journal of obesity (2005) · 2024Article
- Factors Mediating or Moderating the Effects of Obesity on Walking: Targeting Areas for Rehabilitation.Journal of motor behavior · 2024Article
- Biomolecules-Loading of 3D-Printed Alginate-Based Scaffolds for Cartilage Tissue Engineering Applications: A Review on Current Status and Future Prospective.The archives of bone and joint surgery · 2024Review
- Collagen type X expression and chondrocyte hypertrophic differentiation during OA and OS development.American journal of cancer research · 2024Review
- The knee kinematic patterns and associated factors in healthy Thai adults.BMC musculoskeletal disorders · 2023Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
Abstract
backgroundObesity is a mechanical risk factor for osteoarthritis. In individuals with obesity, knee joint pain is prevalent. Weight loss reduces joint loads, and therefore potentially delays disease progression; however, how the knee joint responds to weight loss in individuals with obesity and knee pain is not clear. RESEARCH QUESTION: To assess the effect of weight loss on knee joint kinematics during gait in individuals with obesity and knee pain.
methodsWe recruited individuals with obesity (BMI ≥ 35) and knee pain who were participating in a weight loss program which included bariatric surgery or medical management. At baseline and 1 year follow-up, participants walked on a treadmill, and their knee joint kinematics were assessed using a dual-fluoroscopic imaging system and subject-specific magnetic resonance imaging knee joint models. Gait changes were represented by change in range of tibiofemoral motion, i.e., excursions in flexion-extension, adduction-abduction, internal-external rotation, anterior-posterior translation, medial-lateral translation, and superior-inferior translation during gait.
resultsTwelve individuals with obesity and knee pain completed the gait analysis at baseline and 1 year follow-up. Participants lost on average 10.4% (standard deviation: 17.2%) of their baseline body weight. Reduction in body weight was associated with increased range of flexion-extension (r = -0.75, p < 0.01) and decreased range of adduction-abduction (r = 0.60, p = 0.04) during gait. The reduction in body weight was also associated with self-reported pain decrease (r = 0.62, p = 0.04); however, the change in pain was not significantly associated with kinematic changes. SIGNIFICANCE: Weight loss was associated with improved gait kinematics in the sagittal and frontal planes. The change in gait pattern in individuals with obesity and knee pain was not associated with the change in pain given a reduction in body weight.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.