Evidence map›Paper›PMID 30611305›Full record

ArticleArthritis research & therapy2019

Prevalence and development of hip and knee osteoarthritis according to American College of Rheumatology criteria in the CHECK cohort.

Jurgen Damen, Rogier M van Rijn, Pieter J Emans, Willem K H A Hilberdink, Janet Wesseling, Edwin H G Oei, Sita M A Bierma-Zeinstra

Open access · goldAbstract read
In one paragraph

Article in Arthritis research & therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 5 pooled it
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 5 syntheses or guidelines pooled it, 91 citations in OpenAlex.

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  11. More severe microdamage and micromechanical alterations: altered subchondral bone remodeling in varus knee osteoarthritis with osteoporosis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
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  20. Association between hip pain and radiographic hip osteoarthritis in primary care: the CHECK cohort.The British journal of general practice : the journal of the Royal College of General Practitioners · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Jurgen DamenDepartment of General Practice, Erasmus MC, University Medical Center, PO Box 2040, 3000, CA, Rotterdam, the Netherlands. j.damen@erasmusmc.nl.
Rogier M van RijnNational Institute of Mental Health and Addiction, Trimbos Institute, Utrecht, the Netherlands.
Pieter J EmansDepartment of Orthopaedic Surgery, Maastricht University Medical Center, Maastricht, The Netherlands.
Willem K H A HilberdinkAllied Health Care Center for Rheumatology and Rehabilitation, Groningen, the Netherlands.
Janet WesselingDutch association for Rheumatology, UMC Utrecht, Utrecht, the Netherlands.
Edwin H G OeiDepartment of Radiology & Nuclear Medicine, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Sita M A Bierma-ZeinstraDepartment of General Practice, Erasmus MC, University Medical Center, PO Box 2040, 3000, CA, Rotterdam, the Netherlands.
Erasmus MC · NLMaastricht University · NLTrimbos Institute · NLUniversity Medical Center Utrecht · NL

Funding

Dutch Arthritis Association o
6 · The paper itself

Abstract

backgroundWe aimed to evaluate the prevalence of hip and knee osteoarthritis (HOA and KOA) according to American College of Rheumatology (ACR) criteria among participants with suspected early symptomatic osteoarthritis (OA) in the CHECK cohort. We also assessed whether participants not fulfilling ACR criteria at baseline develop ACR-defined OA at 2-year and/or 5-year follow up, and which baseline factors are associated with this development.

methodsThe CHECK cohort included 1002 subjects with first presentation of knee and/or hip complaints. The primary outcome was onset of HOA and/or KOA according to the ACR criteria, including the clinical classification criteria and the combined clinical and radiographic classification criteria at 2-year and/or 5-year follow up.

resultsOf the participants with hip complaints, 63% (n = 370) were classified as having HOA at baseline according to the ACR criteria. Of those not classified with HOA at baseline, 40% developed HOA according to the clinical or combined clinical/radiographic ACR criteria after 2 and/or 5 years. Up to 92% of participants (n = 829) with knee complaints were classified as having KOA at baseline; of those not classified with KOA at baseline, 55% developed KOA according to the clinical ACR criteria or the clinical/radiographic ACR criteria after 2 and/or 5 years. The following factors were associated with development of HOA: morning stiffness (OR 2.39; 95% CI 1.14-4.98), painful internal rotation (OR 2.53; 95% CI 1.23-5.19), hip flexion < 115° (OR 2.33; 95% CI 1.17-4.64) and erythrocyte sedimentation rate (ESR) < 20 mm/h (OR 2.94; 95% CI 1.13-7.61). No variables were associated with development of KOA at 2-year and/or 5-year follow up.

conclusionsA large proportion of persons with hip complaints not fulfilling the ACR criteria at baseline develop HOA after 2 and/or 5 years of follow up. Almost all persons with knee complaints already fulfill the clinical and/or radiographic ACR criteria for OA, and half of the persons not fulfilling criteria at baseline will do so after 5 years of follow up. Several individual ACR criteria for HOA at baseline were associated with the development of HOA at follow up. This association was not proven for KOA, probably because of the small number of subjects developing KOA in this study.

Indexed as

AgedCohort StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedOsteoarthritis, HipOsteoarthritis, KneePrevalenceProspective StudiesRheumatologyUnited StatesCohortDiagnosticDiagnostic criteriaHipKneeOsteoarthritis

Identifiers

PMID30611305
PMCPMC6321652
OpenAlexW2906853585

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.