Evidence map›Paper›PMID 30611302›Full record

SynthesisImplementation science : IS2019

Systematic review of the Exploration, Preparation, Implementation, Sustainment (EPIS) framework.

Joanna C Moullin, Kelsey S Dickson, Nicole A Stadnick, Borsika Rabin, Gregory A Aarons

4 registry-linked trialsAbstract readSystematic Review
In one paragraph

Synthesis in Implementation science : IS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 696 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
696citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05700890 unknown statusnot on this mapstarted 2023, after this paper: background citation

Adaptation of the World Health Organization Surgical Safety Checklist to High-Income Healthcare Settings - Phase III: Site Testing Study

TypeobservationalSponsorUniversity of CalgaryRan2023 to 2025Enrolled1,000ConditionsSurgical Procedure, Unspecified, Communications Personnel, Tool Use Behavior
NCT06055296 narecruitingnot on this mapstarted 2024, after this paper: background citation

Multisite Implementation of COMPRENDO (ChildhOod Malignancy Peer REsearch NavigatiOn) to Improve Participation of Hispanic Children in Cancer Clinical Trials

TypeinterventionalSponsorUniversity of California, San DiegoRan2024 to 2028Enrolled450ConditionsPediatric CancerArmsCOMPRENDO Peer Navigation Intervention
NCT06941831 narecruitingnot on this mapstarted 2025, after this paper: background citation

Testing an mHealth Digital Dashboard to Improve Quality of Delivery of Evidence-based Interventions That Promote Family Mental Health and Functioning in Rwanda: A Hybrid Type 3 Study

TypeinterventionalSponsorBoston CollegeRan2025 to 2029Enrolled1,810ConditionsIPV, Mental Health, Discipline Practices, Quality AssuranceArmsDigital Dashboard-Supported Sugira Muryango Implementation, Usual Care - Sugira Muryango Implementation
NCT07115030 narecruitingnot on this mapstarted 2026, after this paper: background citation

Project STRONGER: Stepped Care for Opioid Use Disorder Treatment Engagement and Recovery

TypeinterventionalSponsorYale UniversityRan2026 to 2029Enrolled532ConditionsOpioid Use Disorder, Intimate Partner Violence (IPV), Post Traumatic Stress Disorder PTSDArmsPCT+2HOPE
3 · Its place in the literature

Who cites it

696 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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636 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joanna C MoullinFaculty of Health Sciences, School of Pharmacy and Biomedical Sciences, Curtin University, Kent Street, Bentley, Perth, 6102, Western Australia.
Kelsey S DicksonChild and Adolescent Services Research Center, 3665 Kearny Villa Rd., Suite 200N, San Diego, CA, 92123, USA.
Nicole A StadnickChild and Adolescent Services Research Center, 3665 Kearny Villa Rd., Suite 200N, San Diego, CA, 92123, USA.
Borsika RabinDepartment of Family Medicine and Public Health, University of California San Diego, 9500 Gilman Drive (0725), La Jolla, San Diego, CA, 92093-0812, USA.
Gregory A AaronsChild and Adolescent Services Research Center, 3665 Kearny Villa Rd., Suite 200N, San Diego, CA, 92123, USA. gaarons@ucsd.edu.ORCID 0000-0001-8969-5002

Funding

Mixed-Methods Study of EBP Sustainment in a Statewide Service SystemR01MH072961 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AARONS, GREGORY · 2005 to 2016
$5.8M
KIIDS: Knowing about intervention implementation in Detention SitesU01DA036233 · NIDA · EMORY UNIVERSITY · PI DICLEMENTE, RALPH J, SALES, JESSICA A · 2013 to 2017
$3.5M
Testing the Leadership and Organizational Change for Implementation (LOCI) Intervention in Substance Abuse Treatment ProgramsR01DA038466 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AARONS, GREGORY · 2015 to 2019
$3.0M
Adapting and Implementing an Integrated Care Model for Youth with Autism Spectrum Disorder and Psychiatric ComorbidityK23MH110602 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI STADNICK, NICOLE A · 2017 to 2020
$813k
Adapting an ASD Executive Functioning Intervention for Implementation in Children's Mental Health Services - Admin SupplementK23MH115100 · NIMH · SAN DIEGO STATE UNIVERSITY · PI DICKSON, KELSEY S · 2018 to 2021
$730k
Development and Testing of an Evidence Based Intervention Sustainment MeasureR03MH117493 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AARONS, GREGORY · 2018 to 2019
$157k
NIDA NIH HHS R01 DA038466NIDA NIH HHS U01 DA036233NIMH NIH HHS K23 MH110602NIMH NIH HHS K23 MH115100NIMH NIH HHS R01 MH072961NIMH NIH HHS R03 MH117493
6 · The paper itself

Abstract

backgroundEffective implementation of evidence-based practices (EBPs) remains a significant challenge. Numerous existing models and frameworks identify key factors and processes to facilitate implementation. However, there is a need to better understand how individual models and frameworks are applied in research projects, how they can support the implementation process, and how they might advance implementation science. This systematic review examines and describes the research application of a widely used implementation framework, the Exploration, Preparation, Implementation, Sustainment (EPIS) framework.

methodsA systematic literature review was performed to identify and evaluate the use of the EPIS framework in implementation efforts. Citation searches in PubMed, Scopus, PsycINFO, ERIC, Web of Science, Social Sciences Index, and Google Scholar databases were undertaken. Data extraction included the objective, language, country, setting, sector, EBP, study design, methodology, level(s) of data collection, unit(s) of analysis, use of EPIS (i.e., purpose), implementation factors and processes, EPIS stages, implementation strategy, implementation outcomes, and overall depth of EPIS use (rated on a 1-5 scale).

resultsIn total, 762 full-text articles were screened by four reviewers, resulting in inclusion of 67 articles, representing 49 unique research projects. All included projects were conducted in public sector settings. The majority of projects (73%) investigated the implementation of a specific EBP. The majority of projects (90%) examined inner context factors, 57% examined outer context factors, 37% examined innovation factors, and 31% bridging factors (i.e., factors that cross or link the outer system and inner organizational context). On average, projects measured EPIS factors across two of the EPIS phases (M = 2.02), with the most frequent phase being Implementation (73%). On average, the overall depth of EPIS inclusion was moderate (2.8 out of 5).

conclusionThis systematic review enumerated multiple settings and ways the EPIS framework has been applied in implementation research projects, and summarized promising characteristics and strengths of the framework, illustrated with examples. Recommendations for future use include more precise operationalization of factors, increased depth and breadth of application, development of aligned measures, and broadening of user networks. Additional resources supporting the operationalization of EPIS are available.

Indexed as

Evidence-Based PracticeImplementation ScienceDiffusion of InnovationHumansModels, TheoreticalPublic HealthResearch DesignDiffusion of innovationsFrameworkImplementationInner contextModelOuter contextProcessSystematic reviewTheory

Identifiers

PMID30611302
PMCPMC6321673

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.