SynthesisWorld journal of surgical oncology2019
Perioperative transfusion and the prognosis of colorectal cancer surgery: a systematic review and meta-analysis.
Synthesis in World journal of surgical oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Pooled it
- The effect of perioperative blood transfusion on survival after renal cell carcinoma nephrectomy: A systematic review and meta-analysis.Frontiers in oncology · 2023Pooled it
- A systematic review and network meta-analysis comparing energy devices used in colorectal surgery.Techniques in coloproctology · 2022Pooled it
- Determinants of emergency presentation in patients with colorectal cancer: a systematic review and meta-analysis.Scientific reports · 2022Pooled it
- A systematic review of the literature assessing operative blood loss and postoperative outcomes after colorectal surgery.International journal of colorectal disease · 2022Pooled it
- Clinical Implementation and Perioperative Outcomes of Robot-Assisted Pelvic Exenteration for Primary Rectal Cancer: A Multicenter Japanese Experience.Annals of gastroenterological surgery · 2026Article
- Preoperative anemia, transfusions and survival in colorectal cancer surgery-A retrospective study.Wiener klinische Wochenschrift · 2026Article
- Single Cancer Center Experience on Patient Blood Management Eligibility in Oncological Surgery.Journal of clinical medicine · 2026Article
- Perioperative red blood cell transfusion in gallbladder cancer surgery: Trends and determinants from nationwide data.Annals of hepato-biliary-pancreatic surgery · 2025Article
- Prognostic Impact of Postoperative Systemic Immune-Inflammation Index Changes in Epithelial Ovarian Cancer.Cancers · 2025Article
- Development and validation of a predictive model for postoperative pulmonary complications after colorectal cancer surgery: a retrospective study.World journal of surgical oncology · 2025Article
- Robotic versus laparoscopic anterior resection: comparative short-term outcomes in a propensity score matched cohort.Journal of robotic surgery · 2025Article
- Intraoperative Cell Salvage in Oncologic Surgery: A Comprehensive Review.Journal of clinical medicine · 2025Review
- Establishing high risk factors for recurrence in stage I/II colorectal cancer: a metropolitan perspective.World journal of surgical oncology · 2025Article
- Article
- Risk factors for blood transfusion in patients undergoing hysterectomy for stage I endometrial cancer.Langenbeck's archives of surgery · 2025Article
- Construction of a prognostic prediction model for colorectal cancer based on 5-year clinical follow-up data.Scientific reports · 2025Article
- The impact of perioperative anesthesia management-induced immunosuppression on postoperative cancer recurrence and metastasis: a narrative review.Frontiers in oncology · 2025Review
- An overview of the current evidences on the role of iron in colorectal cancer: a review.Frontiers in oncology · 2025Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPerioperative transfusion can reduce the survival rate in colorectal cancer patients. The effects of transfusion on the short- and long-term prognoses are becoming intriguing.
objectiveThis systematic review and meta-analysis aimed to define the effects of perioperative transfusion on the short- and long-term prognoses of colorectal cancer surgery.
resultsThirty-six clinical observational studies, with a total of 174,036 patients, were included. Perioperative transfusion decreased overall survival (OS) (hazard ratio (HR), 0.33; 95% confidence interval (CI), 0.24 to 0.41; P < 0.0001) and cancer-specific survival (CSS) (HR, 0.34; 95% CI, 0.21 to 0.47; P < 0.0001), but had no effect on disease-free survival (DFS) (HR, 0.17; 95% CI, - 0.12 to 0.47; P = 0.248). Transfusion could increase postoperative infectious complications (RR, 1.89, 95% CI, 1.56 to 2.28; P < 0.0001), pulmonary complications (RR, 2.01; 95% CI, 1.54 to 2.63; P < 0.0001), cardiac complications (RR, 2.20; 95% CI, 1.75 to 2.76; P < 0.0001), anastomotic complications (RR, 1.51; 95% CI, 1.29 to 1.79; P < 0.0001), reoperation(RR, 2.88; 95% CI, 2.05 to 4.05; P < 0.0001), and general complications (RR, 1.86; 95% CI, 1.66 to 2.07; P < 0.0001).
conclusionPerioperative transfusion causes a dramatically negative effect on long-term prognosis and increases short-term complications after colorectal cancer surgery.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.