Evidence map›Paper›PMID 30611269›Full record

ArticleBMC complementary and alternative medicine2019

Use of alternative medicine, ginger and licorice among Danish pregnant women - a prospective cohort study.

Tabia Volqvartz, Anna Louise Vestergaard, Sissel Kramer Aagaard, Mette Findal Andreasen, Iana Lesnikova, Niels Uldbjerg, Agnete Larsen, Pinar Bor

Open access · goldAbstract read
In one paragraph

Article in BMC complementary and alternative medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Orally consumed ginger and human health: an umbrella review.The American journal of clinical nutrition · 2022
    Pooled it
  3. Oxidative medicine and cellular longevity · 2021
    Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Tabia VolqvartzDepartment of Obstetrics and Gynecology, Randers Regional Hospital, Randers, Denmark.
Anna Louise VestergaardDepartment of Obstetrics and Gynecology, Randers Regional Hospital, Randers, Denmark.
Sissel Kramer AagaardDepartment of Obstetrics and Gynecology, Randers Regional Hospital, Randers, Denmark.
Mette Findal AndreasenSection for Forensic Chemistry, Department of Forensic Medicine, Aarhus University, Aarhus, Denmark.
Iana LesnikovaDepartment of Pathology, Vidant Medical Center, Greenville, North Carolina, USA.
Niels UldbjergDepartment of Obstetrics and Gynecology, Aarhus University Hospital, Aarhus, Denmark.
Agnete LarsenDepartment of Biomedicine, Pharmacology, Aarhus University, Aarhus, Denmark.
Pinar BorDepartment of Obstetrics and Gynecology, Randers Regional Hospital, Randers, Denmark. isipinbo@rm.dk.
Aarhus University · DKRegional Hospital Randers · DKAarhus University Hospital · DKVidant Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe use of alternative medicines and dietary supplements is constantly changing, as are dietary habits. One example of this phenomenon is the current popularity of ginger products as an everyday health boost. Ginger and licorice has also been shown to ameliorate nausea a common complaint in early pregnancy. Alternative medicines are often regarded as safe. However, they might affect fetal development, such as through alterations of hormone metabolism and cytochrome P450 function. Health care professionals may be unaware of the supplementation habits of pregnant women, which may allow adverse exposures to go unnoticed, especially if the rates of use in pregnancy are not known. We therefore investigated the use of alternative medicines and licorice among pregnant Danish women.

methodsA total of 225 pregnant women were included in a prospective cohort when attending the national prenatal screening program at gestational weeks 10-16. Participants were asked to complete a questionnaire regarding their socio-economic status and lifestyle habits, including their intake of alternative medicine and licorice.

resultsWe found that 22.7% of women reported taking alternative medicines, with 14.7% reporting daily consumption. Ginger supplements were consumed by 11.1%, mainly as health boost and 87.1% reported consumption of licorice. Regular or daily licorice consumption was reported by 38.2 and 7.1%, respectively. Notably, the use of licorice was reflected by an increase in blood pressure of the pregnant women.

conclusionsThe use of licorice and alternative medicines appears to be common in pregnant Danish women, supporting the need for further investigations into the safety of alternative medicine use during pregnancy and the importance of up-to-date personalized counseling regarding popular health trends and lifestyle habits.

Indexed as

GlycyrrhizaPhytotherapyZingiber officinaleDenmarkFemaleHumansMorning SicknessNauseaPlant ExtractsPregnancyPregnancy Trimester, FirstProspective StudiesPlant ExtractsAlternative medicineFirst trimester pregnancyGingerHerbal medicineLicorice

Identifiers

PMID30611269
PMCPMC6320632
OpenAlexW2907425663

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.