Evidence map›Paper›PMID 30611261›Full record

ArticleBMC veterinary research2019

Case report: systemic tuberculosis caused by Mycobacterium bovis in a cat.

Yesari Eroksuz, Ersoy Baydar, Baris Otlu, Murat Dabak, Hatice Eroksuz, Burak Karabulut, Canan Akdeniz Incili, Mehmet Ozkan Timurkan

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC veterinary research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. First Report ofAnimals : an open access journal from MDPI · 2026
    Article
  2. Pathogens (Basel, Switzerland) · 2025
    Review
  3. One health (Amsterdam, Netherlands) · 2025
    Article
  4. Review
  5. Improved detection ofJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2022
    Article
  6. Whole Genome Sequence Analysis ofPathogens (Basel, Switzerland) · 2021
    Article
  7. First report ofJFMS open reports
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Yesari EroksuzDepartment of Pathology, Faculty of Veterinary Medicine, Firat University, 23 200, Elazig, Turkey. yeroksuz@firat.edu.tr.ORCID http://orcid.org/0000-0001-5962-8810
Ersoy BaydarDepartment of Internal Medicine, Faculty of Veterinary Medicine, Balikesir University, Balikesir, Turkey.
Baris OtluDepartment of Medical Microbiology, Faculty of Medicine, Inonu University, Malatya, Turkey.
Murat DabakDepartment of Internal Medicine, Faculty of Veterinary Medicine, Firat University, Elazig, Turkey.
Hatice EroksuzDepartment of Pathology, Faculty of Veterinary Medicine, Firat University, 23 200, Elazig, Turkey.
Burak KarabulutDepartment of Pathology, Faculty of Veterinary Medicine, Firat University, 23 200, Elazig, Turkey.
Canan Akdeniz InciliDepartment of Pathology, Faculty of Veterinary Medicine, Firat University, 23 200, Elazig, Turkey.
Mehmet Ozkan TimurkanDepartment of Virology, Faculty of Veterinary Medicine, Ataturk University, Erzurum, Turkey.
Fırat University · TRAtatürk University · TRBalıkesir University · TRInonu University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe diagnosis of previous cases of feline tuberculosis in Turkey has been made based solely on pathological changes without isolation of the causative agent. This case report details the first case of feline tuberculosis in Turkey for which the causative agent (Mycobacterium bovis) was confirmed with microbiological isolation, morphological evaluation, molecular (PCR) characterization and antibiotic sensitivity. CASE PRESENTATION: Systemic tuberculosis was diagnosed via postmortem examination of a 5-year-old stray male cat. Mycobacterium bovis was isolated from the lungs, bronchial and gastrointestinal lymph nodes, kidney and liver. The isolate was defined as M. bovis using the Genotype MTBC assay (Hain Lifescience, Germany), which allows differentiation of species within the Mycobacterium tuberculosis complex with an easy-to-perform reverse hybridization assay. Pathological changes were characterized by multifocal to coalescing granulomatous inflammation in the lungs, liver, lymph nodes and kidneys. Further pathological changes included severe, diffuse, hepatocytic atrophy, periportal fibrosis with lymphohistiocytic infiltration, multifocal lymphohistiocytic interstitial nephritis, mild focal pulmonary anthracosis and mild renal and hepatic amyloidosis. Infection by immunosuppressive viral pathogens including feline herpes virus-1, feline immunodeficiency virus and feline parvovirus virus were ruled out by polymerase chain reaction assay (PCR). The isolated mycobacteria were susceptible to isoniazid, ethambutol, rifampicin or streptomycin.

conclusionDisseminated M. bovis is a rare infection in cats. Involvement of submandibular lymph nodes suggested that primary transmission might have been the oral route in the present case.

Indexed as

Mycobacterium bovisAnimalsAntineoplastic AgentsCat DiseasesCatsKidneyLungLymph NodesMaleMicrobial Sensitivity TestsTuberculosisTurkeyAntineoplastic AgentsFeline tuberculosisMycobacterium bovisPathological findingsSystemic involvement

Identifiers

PMID30611261
PMCPMC6321719
OpenAlexW2912462907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.