ArticleBMC infectious diseases2019
Development and validation of a risk score to predict mortality during TB treatment in patients with TB-diabetes comorbidity.
Article in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Factors associated with severity of pulmonary tuberculosis in people living with and without HIV: a systematic review.BMC infectious diseases · 2026Pooled it
- Risk prediction models for mortality in patients with multimorbidity: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Systematic review of prediction models for pulmonary tuberculosis treatment outcomes in adults.BMJ open · 2021Pooled it
- Development and validation of clinical prediction score for mortality in tuberculosis patients.Narra J · 2025Article
- Assessment of Risk Factors for Death in Older Adult Patients With TB in Japan.CHEST pulmonary · 2025Article
- Factors influencing drug-susceptible tuberculosis treatment outcomes in Romania and Ukraine.PloS one · 2025Article
- Development and validation of the Tuberculosis Diabetes Mellitus-Predictive Tool (TBDM-PT) in primary care.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2025Article
- Development of prognostic scoring system for predicting 1-year mortality among pulmonary tuberculosis patients in South India.Journal of public health (Oxford, England) · 2023Observational
- A clinical indicator-based prognostic model predicting treatment outcomes of pulmonary tuberculosis: a prospective cohort study.BMC infectious diseases · 2023Article
- Prognostic Score Predicts Survival in HPV-Negative Head and Neck Squamous Cell Cancer Patients.International journal of biological sciences · 2019Article
- Risk factors for mortality among inpatients with smear positive pulmonary tuberculosis.Pakistan journal of medical sciencesArticle
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Authors and funding
2 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundMaking an accurate prognosis for mortality during tuberculosis (TB) treatment in TB-diabetes (TB-DM) comorbid patients remains a challenge for health professionals, especially in low TB prevalent populations, due to the lack of a standardized prognostic model.
methodsUsing de-identified data from TB-DM patients from Texas, who received TB treatment had a treatment outcome of completed treatment or died before completion, reported to the National TB Surveillance System from January 2010-December 2016, we developed and internally validated a mortality scoring system, based on the regression coefficients.
resultsOf 1227 included TB-DM patients, 112 (9.1%) died during treatment. The score used nine characteristics routinely collected by most TB programs. Patients were divided into three groups based on their score: low-risk (< 12 points), medium-risk (12-21 points) and high-risk (≥22 points). The model had good performance (with an area under the receiver operating characteristic (ROC) curve of 0.83 in development and 0.82 in validation), and good calibration. A practical mobile calculator app was also created ( https://oaa.app.link/Isqia5rN6K ).
conclusionUsing demographic and clinical characteristics which are available from most TB programs at the patient's initial visits, our simple scoring system had good performance and may be a practical clinical tool for TB health professionals in identifying TB-DM comorbid patients with a high mortality risk.
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