Evidence map›Paper›PMID 30610881›Full record

ReviewProgress in cardiovascular diseases

Precision Medicine in Weight Loss and Healthy Living.

Richard Severin, Ahmad Sabbahi, Abeer M Mahmoud, Ross Arena, Shane A Phillips

Abstract readReview
In one paragraph

Review in Progress in cardiovascular diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. 360-Degree Perspectives on Obesity.Medicina (Kaunas, Lithuania) · 2023
    Review
  12. Article
  13. 5-HTNutrients · 2023
    Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Richard SeverinDepartment of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, United States of America; Integrated Physiology Laboratory, College of Applied Health Sciences, University of Illinois at Chicago, IL, United States of America; Doctor of Physical Therapy Program, Robbins College of Health and Human Sciences, Baylor University, Waco, TX, United States of America.
Ahmad SabbahiDepartment of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, United States of America; Integrated Physiology Laboratory, College of Applied Health Sciences, University of Illinois at Chicago, IL, United States of America; School of Physical Therapy, South College, Knoxville, TN, United States of America.
Abeer M MahmoudDepartment of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, United States of America; Integrated Physiology Laboratory, College of Applied Health Sciences, University of Illinois at Chicago, IL, United States of America.
Ross ArenaDepartment of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, United States of America; Integrated Physiology Laboratory, College of Applied Health Sciences, University of Illinois at Chicago, IL, United States of America.
Shane A PhillipsDepartment of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, United States of America; Integrated Physiology Laboratory, College of Applied Health Sciences, University of Illinois at Chicago, IL, United States of America. Electronic address: shanep@uic.edu.

Funding

Improving Blood Pressure & Vascular risk with resistance exercise in African AmericansR01HL130513 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI PHILLIPS, SHANE A · 2016 to 2020
$3.5M
Training Program in Personalized Cardiovascular Medicine (TPIPCVM)T32HL139439 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DARBAR, DAWOOD · 2018 to 2022
$2.1M
DNA Methylation and Vascular Function in Obesity: Role of Exercise and Weight LossK99HL140049 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MOHAMED, ABEER M · 2018 to 2019
$213k
NHLBI NIH HHS K99 HL140049NHLBI NIH HHS R01 HL130513NHLBI NIH HHS T32 HL139439
6 · The paper itself

Abstract

Obesity affects 600 million people globally and over one third of the American population. Along with associated comorbidities, including cardiovascular disease, stroke, diabetes, and cancer; the direct and indirect costs of managing obesity are 21% of the total medical costs. These factors shed light on why developing effective and pragmatic strategies to reduce body weight in obese individuals is a major public health concern. An estimated 60-70% of obese Americans attempt to lose weight each year, with only a small minority able to achieve and maintain long term weight loss. To address this issue a precision medicine approach for weight loss has been considered, which places an emphasis on sustainability and real-world application to individualized therapy. In this article we review weight loss interventions in the context of precision medicine and discuss the role of genetic and epigenetic factors, pharmacological interventions, lifestyle interventions, and bariatric surgery on weight loss.

Indexed as

Healthy LifestyleRisk Reduction BehaviorAnti-Obesity AgentsBariatric SurgeryExerciseGenetic Predisposition to DiseaseHealth BehaviorHealth Knowledge, Attitudes, PracticeHealth PromotionHealth StatusHumansObesityPatient-Centered CarePatient Education as TopicPhenotypeProtective FactorsAnti-Obesity AgentsCardiovascular diseaseGeneticsHealthy living interventionPrecision medicineRiskWeight loss

Identifiers

PMID30610881
PMCPMC6546173

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.