ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2019
Patterns, treatments, and outcomes of pediatric central nervous system tumors in Sudan: a single institution experience.
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15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- A system review of central nervous system tumors on children in China: epidemiology and clinical characteristics.BMC cancer · 2024Pooled it
- Global pediatric craniopharyngioma management modalities and outcomes.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Pooled it
- Clinical Landscape and Perception of Surgical Neuro Oncology among Neurosurgical Resident Trainees of Pakistan: A Nationwide Analysis.Pakistan journal of medical sciences · 2025Article
- Childhood cancer survival in low- and middle-income countries and the Global South: emerging evidence and critical gaps from a scoping review of observational studies.EJC paediatric oncology · 2025Review
- Long-term epidemiological trends in (primary) pediatric central nervous system tumors: a 25-year cohort analysis in Western Mexico.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Trends in pediatric CNS tumors in Armenia: a multicenter retrospective study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Feasibility and Safety of Implementing Volumetric Arc Therapy (VMAT) for Pediatric Craniospinal Irradiation in a Low-Middle-Income Region: The Nigerian Experience.Advances in radiation oncology · 2024Article
- How Can Genomic Innovations in Pediatric Brain Tumors Transform Outcomes in Low- and Middle-Income Countries?JCO global oncology · 2022Review
- Surgical outcomes of pediatric brain tumors in Sub-Saharan Africa: A systematic review.Brain & spine · 2022Review
- The landscape of neuro-oncology in East Africa: a review of published records.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Review
- Article
- The Role of Time as a Prognostic Factor in Pediatric Brain Tumors: a Multivariate Survival Analysis.Pathology oncology research : POR · 2020Article
- Pediatric primary central nervous system tumors registry in Thailand under National Health Security Office schemes.Journal of neuro-oncology · 2020Article
- A single well-equipped pediatric oncology center may improve the results in low-/middle-income countries.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019Article
- Neuro-oncology access in Sub-Saharan Africa: A literature review of challenges and opportunities.Neuro-oncology advancesArticle
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeStudies of epidemiology, treatment modalities, and outcomes of childhood central nervous system (CNS) tumors in Sudan are scarce. To address this shortcoming, we evaluated baseline information about the epidemiology, treatment types, and outcomes of childhood CNS tumors at the National Cancer Institute, University of Gezira (NCI-UG) in Wad Madani, Sudan.
methodsWe performed a retrospective health facility-based study of children with CNS tumors who were treated at the NCI-UG from January 2000 to December 2015.
resultsA total of 62 (5.4% of all childhood cancers) pediatric patients with CNS tumors were identified over the study period. Tumors were more common among male children and involved the infratentorial compartment in 58% of cases. The median age at diagnosis was 9 years (range, 2-14 years). Approximately 60% (n = 37) of the study population had histology-determined diagnoses. Astrocytomas and medulloblastomas were the most common tumors in these cases. The mean time to diagnosis was 6 months (SD, 9). During the study period, the number of children with CNS tumors who were referred for treatment at the NCI-UG increased every year. Of the 37 patients who received surgical interventions, 8 received gross total resections, 20 received partial resections, and 24 received postoperative radiotherapy. The treatment abandonment rate was 11%. The 2-year and 5-year survival rates were 33% and 13%, respectively.
conclusionOur findings reveal a high incidence of poor outcomes for patients with CNS tumors in Sudan, which is most likely due to many distinct factors.
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