Evidence map›Paper›PMID 30610477›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2019

A case of central nervous system vasculitis presenting as a mass-like lesion.

AnneMarie M Denny, Sumit K Das

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

AnneMarie M DennyDivision of Pediatric Neurology, University of Alberta Hospital, Edmonton, Alberta, Canada. annemarie.denny@albertahealthservices.ca.ORCID 0000-0002-9317-2690
Sumit K DasDivision of Neuropathology, University of Alberta Hospital, Edmonton, Alberta, Canada.
Alberta Hospital Edmonton · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vasculitis of the central nervous system presenting as a mass lesion is a relatively uncommon occurrence. Even more uncommon is a vasculitis mimicking a demyelinating lesion. We present here an interesting case of a 15-year-old boy who was found to have a mass-like lesion on neuroimaging involving the left subcortical white matter and deep gray matter. The differential diagnosis for this lesion was primary demyelination versus a glial tumor, the former being more favored over the latter. Biopsy of this lesion however revealed findings compatible with a vasculitis, which was unexpected given the neuroimaging findings. To the authors' knowledge, case reports in the English literature of a vasculitic lesion mimicking demyelination are scarce. This case also serves as a reminder of the diagnostic difficulty that arises in a pediatric patient with an initial presentation of mass-like lesion.

Indexed as

AdolescentBrain NeoplasmsDemyelinating DiseasesDiagnosis, DifferentialGliomaGlucocorticoidsHumansMagnetic Resonance ImagingMaleMethylprednisoloneNeuroimagingTreatment OutcomeVasculitis, Central Nervous SystemGlucocorticoidsMethylprednisoloneDemyelinatingMass lesionPrimary angiitis of the central nervous system (PACNS)Tumor-like lesionVasculitis

Identifiers

PMID30610477
OpenAlexW2906821277

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.