SynthesisChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2019
Cranioplasty after craniectomy in pediatric patients-a systematic review.
Synthesis in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Beyond decompression: predictors of cranioplasty failure in pediatric patients - a meta-analysis.Acta neurochirurgica · 2025Pooled it
- Hydrogel Implementing Drug Delivery in Cranial Bone Tissue Engineering.Journal of functional biomaterials · 2026Review
- Pupillomotor Dysfunction and Outcomes After Decompressive Craniectomy in Pediatric Patients.Journal of clinical medicine · 2026Article
- Biomaterials for Regenerative Cranioplasty: Current State of Clinical Application and Future Challenges.Journal of functional biomaterials · 2024Review
- Cranial Repair in Children: Techniques, Materials, and Peculiar Issues.Advances and technical standards in neurosurgery · 2024Review
- Cranial Repair in Children: Techniques, Materials, and Peculiar Issues.Advances and technical standards in neurosurgery · 2024Review
- Analysis of the timing and the usage of drains following cranioplasty on outcomes and the incidence of bone resorption.Surgical neurology international · 2023Article
- Favourable long-term recovery after decompressive craniectomy: the Northern Finland experience with a predominantly adolescent patient cohort.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022Article
- Protocol for the multicentre prospective paediatric craniectomy and cranioplasty registry (pedCCR) under the auspices of the European Society for Paediatric Neurosurgery (ESPN).Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022Article
- From Reparative Surgery to Regenerative Surgery: State of the Art of Porous Hydroxyapatite in Cranioplasty.International journal of molecular sciences · 2022Review
- Comparison of autograft and implant cranioplasty in pediatrics: A meta-analysis.Surgical neurology international · 2022Article
- A Multicentric European Clinical Study on Custom-Made Porous Hydroxyapatite Cranioplasty in a Pediatric Population.Frontiers in surgery · 2022Article
- Bone Flap Resorption in Pediatric Patients Following Autologous Cranioplasty.Operative neurosurgery (Hagerstown, Md.) · 2021Review
- [The latest study on biomimetic mineralized collagen-based bone materials for pediatric skull regeneration and repair].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2021Review
- Time to define what is pediatric in cranial reconstruction.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Article
- Melanotic neuroectodermal tumor of infancy to the skull: case-based review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Review
- Hydroxyapatite ceramic implants for cranioplasty in children: a retrospective evaluation of clinical outcome and osteointegration.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
- Addressing Key Clinical Care and Clinical Research Needs in Severe Pediatric Traumatic Brain Injury: Perspectives From a Focused International Conference.Frontiers in pediatrics · 2020Review
- From decompressive craniectomy to cranioplasty and beyond-a pediatric neurosurgery perspective.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionComplications following cranioplasty with either autografts or cranial implants are commonly reported in pediatric patients. However, data regarding cranioplasty strategies, complications and long-term outcomes are not well described. This study systematically reviews the literature for an overview of current cranioplasty practice in children.
methodsA systematic review of articles published from inception to July 2018 was performed. Studies were included if they reported the specific use of cranioplasty materials following craniectomy in patients younger than 18 years of age, and had a minimum follow-up of at least 1 year.
resultsTwenty-four manuscripts, describing a total of 864 cranioplasty procedures, met the inclusion criteria. The age of patients in this aggregate ranged from 1 month to 20 years and the weighted average was 8.0 years. The follow-up ranged from 0.4 months to 18 years and had a weighted average of 40.4 months. Autologous bone grafts were used in 484 cases (56.0%). Resorption, infection and/or hydrocephalus were the most frequently mentioned complications. In this aggregate group, 61 patients needed a revision cranioplasty. However, in 6/13 (46%) papers studying autologous cranioplasties, no data was provided on resorption, infection and revision cranioplasty rates. Cranial implants were used in 380 cases (44.0%), with custom-made porous hydroxyapatite being the most commonly used material (100/380, 26.3%). Infection and migration/fracturing/loosening were the most frequently documented complications. Eleven revision cranioplasties were reported. Again, no data was reported on infection and revision cranioplasty rates, in 7/16 (44%) and 9/16 (56%) of papers, respectively.
conclusionOur systematic review illuminates that whether autografts or cranial implants are used, postcranioplasty complications are quite common. Beyond this, the existing literature does not contain well documented and comparable outcome parameters, suggesting that prospective, long-term multicenter cohort studies are needed to be able to optimize cranioplasty strategies in children who will undergo cranioplasty following craniectomy.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.