Evidence map›Paper›PMID 30610447›Full record

ArticleInternational journal of legal medicine2019

Coronary artery CT calcium score assessed by direct calcium quantification using atomic absorption spectroscopy and compared to macroscopic and histological assessments.

Alexandra G Gheorghe, Christina Jacobsen, Ragnar Thomsen, Kristian Linnet, Niels Lynnerup, Claus B Andersen, Andreas Fuchs, Klaus F Kofoed, Jytte Banner

Abstract read
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In one paragraph

Article in International journal of legal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Quantitative aortic Na[European journal of nuclear medicine and molecular imaging · 2025
    Article
  4. Article
  5. Article
  6. Article
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  8. Article
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  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexandra G GheorgheSection of Forensic Pathology, Department of Forensic Medicine, University of Copenhagen, Copenhagen, Denmark. svejme@hotmail.com.ORCID http://orcid.org/0000-0003-1682-7865
Christina JacobsenSection of Forensic Pathology, Department of Forensic Medicine, University of Copenhagen, Copenhagen, Denmark.
Ragnar ThomsenSection of Forensic Chemistry, Department of Forensic Medicine, University of Copenhagen, Copenhagen, Denmark.
Kristian LinnetSection of Forensic Chemistry, Department of Forensic Medicine, University of Copenhagen, Copenhagen, Denmark.
Niels LynnerupSection of Forensic Pathology, Department of Forensic Medicine, University of Copenhagen, Copenhagen, Denmark.
Claus B AndersenSection of Forensic Pathology, Department of Forensic Medicine, University of Copenhagen, Copenhagen, Denmark.
Andreas FuchsDepartment of Cardiology, The Heart Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Klaus F KofoedDepartment of Cardiology, The Heart Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Jytte BannerSection of Forensic Pathology, Department of Forensic Medicine, University of Copenhagen, Copenhagen, Denmark.

Funding

361100 361100
6 · The paper itself

Abstract

The Agatston score (AS) is the gold standard CT calcium scoring method in clinical practice. However, the AS is an indirect method of determining calcium amount, whereas atomic absorption spectroscopy (AAS) can directly measure the calcium amount. Our primary aim was to investigate the association between the AS and the coronary calcium amount measured by AAS. Furthermore, we compared our outcome to the macroscopic and histological coronary calcification and stenosis assessment, thus allowing us to infer a clinical coronary artery status based on post-mortem findings. Deceased individuals were examined with a 64-slice multidetector CT scanner, and the AS was determined. At autopsy, the degree of CAC and stenosis was determined, and the coronary arteries were excised and weighed. The coronary arteries were decalcified in a solution that was examined using AAS to measure the calcium amount. The degree of CAC and stenosis was also assessed by a histological examination. One hundred thirty-two coronary arteries were examined, and AS was highly correlated to the coronary calcium amount, measured by AAS, (r

Indexed as

AutopsyCalciumCoronary StenosisCoronary VesselsCorrelation of DataFemaleHumansMaleMultidetector Computed TomographySpectrophotometry, AtomicVascular CalcificationCalciumAgatston scoreAtomic absorption spectroscopyCalcium scoringCoronary artery calcificationCoronary artery diseaseCoronary calcium scoring method

Identifiers

PMID30610447

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.