ArticleJournal of neurology2019
Impact of virtual reality-based rehabilitation on functional outcomes in patients with acute stroke: a retrospective case-matched study.
Article in Journal of neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07723755 (The Effectiveness of Using Interactive Devices for Home Exercise in Patients With Frozen Shoulder.), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effectiveness of Using Interactive Devices for Home Exercise in Patients With Frozen Shoulder.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Examining the effectiveness of virtual, augmented, and mixed reality (VAMR) therapy for upper limb recovery and activities of daily living in stroke patients: a systematic review and meta-analysis.Journal of neuroengineering and rehabilitation · 2022Pooled it
- Ankle injury rehabilitation and place of immersive virtual reality as digital health solutions in rehabilitation: A clinical randomized controlled trial.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2026Trial
- Effects of Virtual Reality-Based Therapy on Quality of Life of Patients with Subacute Stroke: A Three-Month Follow-Up Randomized Controlled Trial.International journal of environmental research and public health · 2021Trial
- Effects of Video-Game Based Therapy on Balance, Postural Control, Functionality, and Quality of Life of Patients with Subacute Stroke: A Randomized Controlled Trial.Journal of healthcare engineering · 2020Trial
- Value of Robotics: Comparison of Three Different High-Intensity Training Programs for Rehabilitation After Stroke.Sensors (Basel, Switzerland) · 2025Article
- A preliminary study of the reliability and validity of the Uyghur version of the NUCOG cognitive screening application.BMC neurology · 2025Article
- Effective unilateral/bilateral robot-assisted training for upper limb motor function rehabilitation: a cross-sectional study.Frontiers in human neuroscience · 2025Article
- Article
- Characterization of Upper Extremity Kinematics Using Virtual Reality Movement Tasks and Wearable IMU Technology.Sensors (Basel, Switzerland) · 2023Article
- Design and Validation of Virtual Reality Task for Neuro-Rehabilitation of Distal Upper Extremities.International journal of environmental research and public health · 2022Article
- Kinect-Based Rehabilitation Systems for Stroke Patients: A Scoping Review.BioMed research international · 2022Article
- Effects of Specific Virtual Reality-Based Therapy for the Rehabilitation of the Upper Limb Motor Function Post-Ictus: Randomized Controlled Trial.Brain sciences · 2021Article
- Economic Evaluation in Neurological Physiotherapy: A Systematic Review.Brain sciences · 2021Review
- Stroke Dysbiosis Index (SDI) in Gut Microbiome Are Associated With Brain Injury and Prognosis of Stroke.Frontiers in neurology · 2019Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
BACKGROUND AND
objectivesTo date, the efficacy of the virtual reality (VR) application for acute stroke compared with conventional therapy (CT) remains unclear. This retrospective study aims to assess the impact of adjuvant VR technology on multidimensional therapy for patients with acute-stage stroke.
methods100 acute ischemic stroke patients with onset within 7 days who underwent combined adjuvant VR-based rehabilitation program and CT (intervention group-VR + CT) were compared to an equal number of cross-matched patients who received CT alone. While the intervention group received 40-min CT plus 20-min VR program (seven times for 1 week), the comparison group received time-matched CT alone. The National Institutes of Health Stroke Scale (NIHSS), modified Rankin Scale (mRS), medical cost-effectiveness, and shortening of hospital stay were used as outcome measures.
resultsPosttreatment, the VR + CT group revealed significantly improved NIHSS and mRS (P < 0.001), whereas only the mRS improvement was remarkable in the CT group. In between-group comparisons, the intervention group had better improvements of symptom severity (NIHSS percentage improvement from the baseline; 20.18% vs. 4.59%, P < 0.005), functional outcomes (mRS improvement from the baseline; - 0.58 vs. - 0.23, P < 0.001), and reduced medical cost (Taiwan dollar; 49474 vs. 66306, P < 0.005). Furthermore, the VR + CT group reached markedly higher proportion of functional independence in activities of daily living (mRS, 0-2) at discharge compared with the CT group (68% vs. 60%, P < 0.001).
conclusionsThis study suggests that the combination of VR-based rehabilitation and traditional therapy could be more effective for neurorehabilitation than CT alone in the early improvement of symptom severity, functional outcomes, and lower medical expenditure in acute stroke patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.