ArticleWorld journal of urology2019
Endoscopic observations as a tool to define underlying pathology in kidney stone formers.
Article in World journal of urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Novel insights into the role of the renal interstitial microenvironment in Randall's plaque formation (Review).International journal of molecular medicine · 2026Review
- Visual assessment of Randall's plaque using traxer grading and its correlations with demographic characteristics, metabolic parameters and stone analysis.World journal of urology · 2026Article
- FASLG Derived from Fibroblasts in Hydroxyapatite-Rich Microenvironment Induces Urothelial Anoikis to Trigger Randall's Plaque Exposure.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Validation of a Renal Papillary Grading System: Comparison of Patients Forming Calcium Oxalate and Apatite Stones.Journal of endourology · 2026Article
- Understanding intrarenal backflow: Intrarenal pressure during ureteroscopy and beyond.Asian journal of urology · 2024Article
- Risk factors and predictors of urogenous sepsis after percutaneous nephrolithotomy for idiopathic calcium oxalate nephrolithiasis.Translational andrology and urology · 2023Article
- Endoscopic Papillary Abnormalities and Stone Recognition (EPSR) during Flexible Ureteroscopy: A Comprehensive Review.Journal of clinical medicine · 2021Review
- Construction and Analysis of Immune Infiltration-Related ceRNA Network for Kidney Stones.Frontiers in genetics · 2021Article
- Automatic detection of calcium phosphate deposit plugs at the terminal ends of kidney tubules.Healthcare technology letters · 2019Article
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Authors and funding
7 authors.
Funding
Abstract
purposeAdvancements in endoscopy offer the possibility of inspection of intrarenal anatomy and pathology. The aim of the study was to evaluate renal papillary appearance in kidney stone formers and to correlate papillary findings with stone type and patient metabolic data. MATERIALS AND
methodsA consecutive cohort of 46 kidney stone formers undergoing retrograde intrarenal surgery was enrolled. During surgery, renal papillae were characterized in the domains of ductal Plugging (DP), surface Pitting, Loss of papillary contour, and Amount of Randall's plaque (RP, PPLA scoring). Stone material was analyzed using micro-CT and infrared spectroscopy, and blood and urine were collected for metabolic evaluation.
resultsIn all patients, renal papillae had changes in at least one of the domains of the PPLA score. Examining the total population, it was evident that patients with predominantly plugging (DP > 0) all had very low RP scores. There were no significant trends between mean PPLA scores and urinary analytes for the total group.
conclusionEfforts to prevent renal stone formation have so far been insufficient in majority of patients. Digital endoscopy reveals that kidney stone formers have different and distinct papillary morphologies that seem to be linked to specific stone-forming pathways. Since renal papillary abnormalities may be easily identified during endoscopy, this may in the future prove to be an important method for tailoring prevention strategies in kidney stone patients.
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