Evidence map›Paper›PMID 30610356›Full record

ArticleStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2019

Predicting tumor responses and patient survival in chemoradiotherapy-treated patients with non-small-cell lung cancer using dynamic contrast-enhanced integrated magnetic resonance-positron-emission tomography.

Yu-Sen Huang, Jenny Ling-Yu Chen, Jo-Yu Chen, Yee-Fan Lee, Jei-Yie Huang, Sung-Hsin Kuo, Ruoh-Fang Yen, Yeun-Chung Chang

Abstract read
PubMed Publisher
In one paragraph

Article in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
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  4. Article
  5. Article
  6. Preclinical evaluation of PEGylated liposomal doxorubicin as an effective radiosensitizer in chemoradiotherapy for lung cancer.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yu-Sen HuangDepartment of Medical Imaging, National Taiwan University Hospital, National Taiwan University College of Medicine, No.7, Chung-Shan South Road, 100, Taipei, Taiwan.
Jenny Ling-Yu ChenInstitute of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, Taiwan.
Jo-Yu ChenDepartment of Medical Imaging, National Taiwan University Hospital, National Taiwan University College of Medicine, No.7, Chung-Shan South Road, 100, Taipei, Taiwan.
Yee-Fan LeeDepartment of Medical Imaging, National Taiwan University Hospital, National Taiwan University College of Medicine, No.7, Chung-Shan South Road, 100, Taipei, Taiwan.
Jei-Yie HuangDepartment of Nuclear Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.
Sung-Hsin KuoDepartment of Oncology, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.
Ruoh-Fang YenDepartment of Nuclear Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.
Yeun-Chung ChangDepartment of Medical Imaging, National Taiwan University Hospital, National Taiwan University College of Medicine, No.7, Chung-Shan South Road, 100, Taipei, Taiwan. ycc5566@ntu.edu.tw.

Funding

Ministry of Science and Technology, Taiwan MST 100-2221-E-002-031-MY3, 104-2221-E-002-093-MY3, and 107-2314-B-002-225-MY2National Taiwan University Hospital NTUH106-N3662, NTUH107-M4007
6 · The paper itself

Abstract

purposeWe investigated whether radiologic parameters by dynamic contrast-enhanced (DCE) integrated magnetic resonance-positron-emission tomography (MR-PET) predicts tumor response to treatment and survival in non-metastatic non-small-cell lung cancer (NSCLC) patients receiving chemoradiotherapy (CRT).

methodsPatients underwent DCE integrated MR-PET imaging 1 week before CRT. The following parameters were analyzed: primary tumor size, gross tumor volume, maximal standardized uptake value (SUV

resultsThirty patients were included. Non-responders demonstrated higher baseline TLG (p = 0.012), and lower baseline K

conclusionsThe radiologic parameters derived from DCE integrated MR-PET scans are useful for predicting treatment response in NSCLC patients treated with CRT; furthermore, these parameters are correlated with clinical and survival outcomes including tumor progression and death.

Indexed as

Image EnhancementAdultAgedAged, 80 and overCarcinoma, Non-Small-Cell LungChemoradiotherapyContrast MediaFemaleHumansLung NeoplasmsMagnetic Resonance ImagingMaleMiddle AgedNeoplasm StagingPositron-Emission TomographyPredictive Value of TestsContrast MediaGlycolysisMagnetic resonance imagingNeoplasmsProgression-free survivalTherapeutic uses

Identifiers

PMID30610356

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.