ArticleNaunyn-Schmiedeberg's archives of pharmacology2019
Chavibetol corrects thyrotoxicosis through alterations in thyroid peroxidase.
Article in Naunyn-Schmiedeberg's archives of pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 14 citations in OpenAlex.
- Role of thyroid peroxidase in health and disease: A comprehensive update on TPO gene and protein expression, enzymatic activity and pharmacological modulation.Reviews in endocrine & metabolic disorders · 2026Review
- Decoding the effect of Diceratella elliptica on the oxidative stress-Inflammation axis in hyperthyroid-induced hepatotoxicity.Journal, genetic engineering & biotechnology · 2025Article
- Protective Effects of Hemp (Molecules (Basel, Switzerland) · 2023Article
- Evaluation of antithyroid potential ofJournal of food science and technology · 2020Article
- Ameliorative effect of Aloe gel against L-TMolecular biology reports · 2020Article
- Allylpyrocatechol, isolated from betel leaf ameliorates thyrotoxicosis in rats by altering thyroid peroxidase and thyrotropin receptors.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thyrotoxicosis is a clinical syndrome that commonly results from excess secretion and/or release of thyroid hormones in the circulation. It affects most of the body systems and if not treated properly may lead to serious health problems. In this investigation, we isolated a phenolic compound, chavibetol (CHV) from Piper betel leaf and evaluated its possible ameliorative effects in thyrotoxicosis of rats. Adult female rats were rendered thyrotoxic by the administration of L-thyroxine (L-T
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Registered trials
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